SCHEMBL1981815

SCHEMBL1981815

CC(F)(Cl)C(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8952521 0.80 ALDH1A1 (0.41)
SCHEMBL9292279 0.80 ALDH1A1 (0.41)
SCHEMBL1994107 0.78
SCHEMBL9575995 0.75
SCHEMBL5011959 0.75
SCHEMBL12265117 0.75
SCHEMBL1994642 0.75
SCHEMBL28939798 0.75
SCHEMBL6905787 0.74 ALDH1A1 (0.37)
SCHEMBL28941 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1943202-B1 METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUNDS HONEYWELL INT INC (US) 2014-12-17 EP disclosed
EP-2374782-B1 PROCESSES FOR PRODUCING 2-CHLORO-1,1,1,2-TETRAFLUOROPROPANE AND 2,3,3,3-TETRAFLUOROPROPENE ASAHI GLASS CO LTD (JP) 2014-09-17 EP disclosed
US-8395001-B2 Processes for producing 2-chloro-1,1,1,2-tetrafluoropropane and 2,3,3,3-tetrafluoropropene ASAHI GLASS COMPANY, LIMITED (JP) 2013-03-12 US disclosed
EP-2374782-A1 PROCESSES FOR PRODUCING 2-CHLORO-1,1,1,2-TETRAFLUOROPROPANE AND 2,3,3,3-TETRAFLUOROPROPENE Asahi Glass Company Limited (JP) 2011-10-12 EP disclosed
US-20110237846-A1 PROCESSES FOR PRODUCING 2-CHLORO-1,1,1,2-TETRAFLUOROPROPANE AND 2,3,3,3-TETRAFLUOROPROPENE ASAHI GLASS COMPANY, LIMITED (JP) 2011-09-29 US disclosed
EP-2336102-A1 Method for producing fluorinated organic compounds Honeywell International Inc. (US) 2011-06-22 EP disclosed
US-7659434-B2 Contacting hydrogen fluoride with 1,1,1,2-tetrachloro-2-fluoro-propaneto produce 2-chloro-3,3,3-trifluoropropene (HCFC-241bb) and 2,3,3,3-tetrafluoropropene; dehydrohalogenation in the vapor phase using a catalyst of ferric chloride on a carbon support; catalyst selectivity;cost efficiency HONEYWELL INTERNATIONAL INC. (US) 2010-02-09 US disclosed
EP-1943202-A1 METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUNDS Honeywell International, Inc. (US) 2008-07-16 EP disclosed
WO-2007056148-A1 METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUNDS HONEYWELL INTERNATIONAL INC. (US) 2007-05-18 WO disclosed
US-20070112228-A1 Method for producing fluorinated organic compounds HONEYWELL INTERNATIONAL INC. (US) 2007-05-17 US disclosed
US-5264639-A Fluorination of chlorine containing 2,2-halogenopropane with hydrogen fluoride ASAHI GLASS COMPANY LTD. (JP) 1993-11-23 US disclosed
EP-0407622-A1 PROCESS FOR PRODUCING A 2,2-DIFLUOROPROPANE. ASAHI GLASS CO LTD (JP) 1991-01-16 EP disclosed
WO-1990008754-A2 PROCESS FOR PRODUCING A 2,2-DIFLUOROPROPANE ASAHI GLASS COMPANY LTD. (JP) 1990-08-09 WO disclosed