SCHEMBL6905787

SCHEMBL6905787

CC(F)(Cl)C(Cl)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6903942 0.76 ALDH1A1 (0.39) ALDH1A1HSD17B10
SCHEMBL1981815 0.74
SCHEMBL3269338 0.73 ALDH1A1 (0.50) ALDH1A1HSD17B10
SCHEMBL407693 0.73 ALDH1A1 (0.50) ALDH1A1HSD17B10
SCHEMBL3845474 0.72 ALDH1A1 (0.41) ALDH1A1HSD17B10
SCHEMBL8952521 0.72 ALDH1A1 (0.41) ALDH1A1HSD17B10TSHR
SCHEMBL1990356 0.72 ALDH1A1 (0.41) ALDH1A1HSD17B10
SCHEMBL8157111 0.72 ALDH1A1 (0.41) ALDH1A1HSD17B10
SCHEMBL9292279 0.72 ALDH1A1 (0.41) ALDH1A1HSD17B10TSHR
SCHEMBL16241278 0.71 ALDH1A1 (0.35) ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6702929-B2 Purification of 1,1,1,3,3-pentafluorobutane HONEYWELL INTERNATIONAL INC. 2004-03-09 US claimed
EP-1341744-A1 PURIFICATION OF 1,1,1,3,3-PENTAFLUOROBUTANE Honeywell International Inc. (US) 2003-09-10 EP claimed
US-20030111332-A1 Purification of 1,1,1,3,3-pentafluorobutane HONEYWELL INTERNATIONAL INC. 2003-06-19 US claimed
WO-2002060845-A1 PURIFICATION OF 1,1,1,3,3-PENTAFLUOROBUTANE HONEYWELL INTERNATIONAL INC. (US) 2002-08-08 WO claimed
US-20020077513-A1 Purification of 1,1,1,3,3-pentafluorobutane HONEYWELL INTERNATIONAL INC. 2002-06-20 US claimed
US-6702929-B2 Purification of 1,1,1,3,3-pentafluorobutane HONEYWELL INTERNATIONAL INC. 2004-03-09 US disclosed
US-6702929-B2 Purification of 1,1,1,3,3-pentafluorobutane HONEYWELL INTERNATIONAL INC. 2004-03-09 US disclosed
EP-1341744-A1 PURIFICATION OF 1,1,1,3,3-PENTAFLUOROBUTANE Honeywell International Inc. (US) 2003-09-10 EP disclosed
EP-1341744-A1 PURIFICATION OF 1,1,1,3,3-PENTAFLUOROBUTANE Honeywell International Inc. (US) 2003-09-10 EP disclosed
US-20030111332-A1 Purification of 1,1,1,3,3-pentafluorobutane HONEYWELL INTERNATIONAL INC. 2003-06-19 US disclosed
US-20030111332-A1 Purification of 1,1,1,3,3-pentafluorobutane HONEYWELL INTERNATIONAL INC. 2003-06-19 US disclosed
WO-2002060845-A1 PURIFICATION OF 1,1,1,3,3-PENTAFLUOROBUTANE HONEYWELL INTERNATIONAL INC. (US) 2002-08-08 WO disclosed
WO-2002060845-A1 PURIFICATION OF 1,1,1,3,3-PENTAFLUOROBUTANE HONEYWELL INTERNATIONAL INC. (US) 2002-08-08 WO disclosed
US-20020077513-A1 Purification of 1,1,1,3,3-pentafluorobutane HONEYWELL INTERNATIONAL INC. 2002-06-20 US disclosed
US-20020077513-A1 Purification of 1,1,1,3,3-pentafluorobutane HONEYWELL INTERNATIONAL INC. 2002-06-20 US disclosed