Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19820104 | 1.00 | CTSS (0.43) | CTSSCTSKCA1CA2CAPN1 | |
| SCHEMBL23626318 | 0.90 | CTSK (0.49) | CTSSCTSKCA1CA2CAPN1 | |
| SCHEMBL21506938 | 0.90 | CTSK (0.45) | CTSSCTSKCA1CA2CAPN1 | |
| SCHEMBL16504609 | 0.89 | CTSS (0.48) | CTSSCTSKCA1CA2CAPN1 | |
| SCHEMBL16572281 | 0.89 | CTSS (0.48) | CTSSCTSKCA1CA2CAPN1 | |
| SCHEMBL16504508 | 0.89 | CTSS (0.48) | CTSSCTSKCA1CA2CAPN1 | |
| SCHEMBL16504607 | 0.89 | CTSS (0.48) | CTSSCTSKCA1CA2CAPN1 | |
| SCHEMBL16572287 | 0.89 | CTSS (0.48) | CTSSCTSKCA1CA2CAPN1 | |
| SCHEMBL16504677 | 0.89 | CTSS (0.48) | CTSSCTSKCA1CA2CAPN1 | |
| SCHEMBL16504678 | 0.89 | CTSS (0.48) | CTSSCTSKCA1CA2CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9878988-B2 | Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases | PARION SCIENCES, INC. (US) | 2018-01-30 | — | — | US | disclosed |