⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19820996 | 0.81 | ABCC4 (0.39) | — | |
| SCHEMBL19820968 | 0.81 | MAOA (0.35) | — | |
| SCHEMBL19820982 | 0.78 | KCNN4 (0.31) | — | |
| SCHEMBL19820941 | 0.77 | L3MBTL1 (0.31) | — | |
| SCHEMBL19820946 | 0.77 | KCNN4 (0.34) | — | |
| SCHEMBL19820997 | 0.75 | — | — | |
| SCHEMBL19820999 | 0.75 | — | — | |
| SCHEMBL19821001 | 0.69 | KCNN4 (0.35) | — | |
| SCHEMBL19821009 | 0.68 | — | — | |
| SCHEMBL24156390 | 0.67 | TRPV1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10183917-B2 | Tricyclic compounds and uses thereof in medicine | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-01-22 | — | — | US | disclosed |
| US-20180030003-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-02-01 | — | — | US | disclosed |