SCHEMBL19821806

SCHEMBL19821806

CCC(C)(C)C(=O)OCC(O)CC(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 4/20 0.37
BIRC2 Q13490 1/20 0.33
ADRB2 P07550 4/20 0.32
ADRB1 P08588 4/20 0.32
ADRB3 P13945 4/20 0.32
LMNA P02545 2/20 0.32
KDM4E B2RXH2 1/20 0.32
DUSP3 P51452 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TET2 Q6N021 1/20 0.32
LPAR6 P43657 1/20 0.31
LPAR1 Q92633 1/20 0.31
LPAR4 Q99677 1/20 0.31
LPAR5 Q9H1C0 1/20 0.31
LPAR2 Q9HBW0 1/20 0.31
LPAR3 Q9UBY5 1/20 0.31
ENPP2 Q13822 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12135548 0.84 HMGCR (0.40) HMGCRADRB2ADRB1ADRB3LMNA
SCHEMBL26363187 0.83 HMGCR (0.50) HMGCRLMNA
SCHEMBL19821865 0.82 HMGCR (0.36) HMGCRADRB2ADRB1ADRB3LMNA
SCHEMBL25813535 0.82 HMGCR (0.36) HMGCRLMNAKDM4EDUSP3MEN1
SCHEMBL26363333 0.81 HMGCR (0.38) HMGCRADRB2ADRB1ADRB3LMNA
SCHEMBL10017776 0.81 HMGCR (0.36) HMGCRADRB2ADRB1ADRB3LMNA
SCHEMBL8986670 0.80 HMGCR (0.41) HMGCRADRB2ADRB1ADRB3LMNA
SCHEMBL19821927 0.80 HMGCR (0.35) HMGCRADRB2ADRB1ADRB3
SCHEMBL19428724 0.79 HMGCR (0.37) HMGCRADRB2ADRB1ADRB3LMNA
SCHEMBL116867 0.79 LMNA (0.46) HMGCRLMNAKDM4EDUSP3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230129965-A1 HYDROPHILIC AND OLEOPHOBIC POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-04-27 US disclosed
US-20180030175-A1 POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-01 US disclosed