Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16059041 | 0.73 | MAPK1 (0.39) | KMT2AADORA3ADORA2AADORA1 | |
| SCHEMBL22873524 | 0.70 | — | — | |
| SCHEMBL13165484 | 0.69 | PDE10A (0.36) | KMT2AADORA3PDE10AADORA2AADORA1 | |
| SCHEMBL17625052 | 0.69 | KMT2A (0.36) | KMT2AADORA3PDE10AADORA2AADORA1 | |
| SCHEMBL13184884 | 0.69 | PDE4A (0.41) | KMT2AADORA3PDE10AADORA2AADORA1 | |
| SCHEMBL23599060 | 0.68 | CA1 (0.54) | AXL | |
| SCHEMBL1061432 | 0.67 | CA1 (0.50) | KMT2APDE10AADORA1 | |
| SCHEMBL16714483 | 0.67 | KMT2A (0.44) | KMT2AADORA3PDE10AADORA2AADORA1 | |
| SCHEMBL21554085 | 0.66 | POLB (0.40) | KMT2AADORA3ADORA2AADORA1AXL | |
| SCHEMBL29953279 | 0.66 | PDE10A (0.54) | PDE10APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970266-B1 | 1-PHENOXY-3-(ALKYLAMINO)-PROPAN-2-OL DERIVATIVES AS CARM1 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2018-01-31 | — | — | EP | disclosed |