Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13184884 | 0.72 | PDE4A (0.41) | PDE10AKMT2APDE4AEHMT2ADORA3 | |
| SCHEMBL501400 | 0.72 | ALDH1A1 (0.39) | PDE4A | |
| SCHEMBL12526927 | 0.69 | CYP1A2 (0.40) | PDE10AKMT2A | |
| SCHEMBL17625052 | 0.69 | KMT2A (0.36) | PDE10AKMT2APDE4AEHMT2ADORA3 | |
| SCHEMBL19822682 | 0.69 | KMT2A (0.36) | PDE10AKMT2APDE4AEHMT2ADORA3 | |
| Hydrochloric Acid SCHEMBL1748472 | 0.68 | CYP1A2 (0.39) | PDE10AKMT2A | |
| SCHEMBL14852943 | 0.67 | PDE10A (0.51) | PDE10AKMT2APDE4ACHRM3PDE4B | |
| SCHEMBL16714483 | 0.67 | KMT2A (0.44) | PDE10AKMT2APDE4AADORA3ADORA2A | |
| SCHEMBL21554085 | 0.66 | POLB (0.40) | KMT2AADORA3ADORA2AADORA1AXL | |
| SCHEMBL28537305 | 0.65 | KDM4E (0.40) | PDE10AKMT2APDE4AADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803821-B2 | N-cyclopropyl-N-[(3,4-dimethoxypyridin-2-yl)methyl]-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide; control of phytopathogenic fungi of plants | BAYER CROPSCIENCE SA (FR) | 2010-09-28 | — | — | US | disclosed |
| US-20090270461-A1 | Fungicide n-cycloalkyl-carboxamide, thiocarboxamide and n-substituted-carboximidamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270461-A1 | Fungicide n-cycloalkyl-carboxamide, thiocarboxamide and n-substituted-carboximidamide derivatives | NRDC, CBR3, NR2C2 | PDE10A 2679/4885KMT2A 2347/4885PDE4A 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.