Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | KIF5B | P33176 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19825489 | 0.80 | TLR9 (0.41) | PTGS2HCRTR1HCRTR2MCL1MEN1 | |
| SCHEMBL16269464 | 0.76 | ERN1 (0.35) | EGFRRETKIF5BKDRMAOB | |
| SCHEMBL16269432 | 0.75 | TACR1 (0.37) | MAOBKDM1A | |
| SCHEMBL16268503 | 0.72 | NPSR1 (0.39) | PTGS2MAOBKDM1A | |
| SCHEMBL16269729 | 0.71 | ALDH1A1 (0.34) | KDM1ACYP3A4 | |
| SCHEMBL16268914 | 0.70 | KDM1A (0.36) | CNR2KDM1A | |
| SCHEMBL16269585 | 0.70 | KDM1A (0.32) | KDM1A | |
| SCHEMBL16554380 | 0.69 | GAA (0.37) | KMT2AKDM1A | |
| SCHEMBL23603848 | 0.67 | KDM1A (0.35) | EGFRRETKIF5BKDRMEN1 | |
| SCHEMBL19825434 | 0.66 | TLR9 (0.33) | HCRTR1HCRTR2TLR9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004043-B1 | HERBICIDALLY ACTIVE (ALKYNYL-PHENYL)-SUBSTITUTED CYCLIC DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2018-01-31 | — | — | EP | disclosed |