Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PPOX | P50336 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16269432 | 0.94 | TACR1 (0.37) | NPSR1CA1CA2CA4CA6 | |
| SCHEMBL15821759 | 0.82 | CA1 (0.35) | NPSR1CA1CA2CA4CA6 | |
| SCHEMBL16269464 | 0.80 | ERN1 (0.35) | NPSR1TACR1KDM1AHTR2AERN1 | |
| SCHEMBL16554380 | 0.79 | GAA (0.37) | NPSR1TACR1KDM1AALDH1A1PPOX | |
| SCHEMBL16271870 | 0.78 | PPOX (0.32) | CA1CA2CA4CA6PTGS2 | |
| SCHEMBL16268914 | 0.77 | KDM1A (0.36) | NPSR1KDM1AHTR2AERN1 | |
| SCHEMBL16269585 | 0.74 | KDM1A (0.32) | NPSR1KDM1AERN1ALDH1A1 | |
| SCHEMBL11224580 | 0.73 | TDP1 (0.33) | — | |
| SCHEMBL16269729 | 0.72 | ALDH1A1 (0.34) | KDM1AERN1ALDH1A1 | |
| SCHEMBL19825533 | 0.72 | PTGS2 (0.34) | KDM1APTGS2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696686-B2 | Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2020-06-30 | — | — | US | disclosed |
| EP-3004043-B1 | HERBICIDALLY ACTIVE (ALKYNYL-PHENYL)-SUBSTITUTED CYCLIC DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2018-01-31 | — | — | EP | disclosed |
| US-20160207934-A1 | Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2016-07-21 | — | — | US | disclosed |
| US-20160207934-A1 | Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2016-07-21 | — | — | US | disclosed |
| US-20160207934-A1 | Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2016-07-21 | — | — | US | disclosed |
| EP-3004043-A1 | HERBICIDALLY ACTIVE (ALKYNYL-PHENYL)-SUBSTITUTED CYCLIC DIONE COMPOUNDS AND DERIVATIVES THEREOF | Syngenta Limited (GB) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014191534-A1 | HERBICIDALLY ACTIVE (ALKYNYL-PHENYL)-SUBSTITUTED CYCLIC DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LIMITED (GB) | 2014-12-04 | — | — | WO | disclosed |
| WO-2014191534-A1 | HERBICIDALLY ACTIVE (ALKYNYL-PHENYL)-SUBSTITUTED CYCLIC DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LIMITED (GB) | 2014-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696686-B2 | Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof | DDT, CNPY2, CNPY3 | NPSR1 4364/4885CA1 583/4885CA2 183/4885 |
| US-20160207934-A1 | Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof | DDT, CNPY2, CNPY3 | NPSR1 4364/4885CA1 583/4885CA2 183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.