SCHEMBL19826542

SCHEMBL19826542

COC(=O)NCCCn1nc(C(C)N(C(=O)[C@H]2CN[C@@H](CO)CO2)C2CC2)c2ccc(C)nc21

nearest known ligand 0.78

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17013827 1.00 REN (0.78) REN
SCHEMBL17013767 0.94 REN (0.77) REN
SCHEMBL17005385 0.94 REN (0.68) REN
SCHEMBL17013714 0.93 REN (0.76) REN
SCHEMBL17013664 0.93 REN (0.75) REN
SCHEMBL17013667 0.93 REN (0.75) REN
SCHEMBL17013674 0.92 REN (0.74) REN
SCHEMBL17013791 0.90 REN (0.71) REN
SCHEMBL17013073 0.89 REN (0.70) REN
Sitokiren SCHEMBL19512247 0.87 REN (1.00) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2933248-B1 NOVEL RENIN INHIBITOR MITSUBISHI TANABE PHARMA CORP (JP) 2018-01-31 — — EP disclosed
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