Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.41 |
| ▸ | MAOA | P21397 | 7/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19828084 | 0.81 | POLB (0.43) | SLC6A2SLC6A4CYP2D6SLC6A3 | |
| Hydrochloric Acid SCHEMBL29960736 | 0.79 | HTR2A (0.47) | SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL19830037 | 0.77 | MAOB (0.61) | MAOBMAOABCHEADRA2BADRA2C | |
| SCHEMBL19827901 | 0.77 | MAOB (0.61) | MAOBMAOABCHEADRA2BADRA2C | |
| SCHEMBL19830012 | 0.77 | MAOB (0.61) | MAOBMAOABCHEADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL29960694 | 0.75 | HTR2C (0.38) | SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL8367488 | 0.75 | HTR2A (0.34) | SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL19828037 | 0.73 | MAOB (0.40) | MAOBMAOABCHEADRA2BADRA2C | |
| SCHEMBL2475073 | 0.73 | MAOB (0.51) | MAOBMAOABCHEADRA2BADRA2C | |
| SCHEMBL7950524 | 0.72 | MTNR1A (0.33) | MAOBMAOAHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018023070-A1 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SUNOVION PHARMACEUTICALS, INC. (US) | 2018-02-01 | — | — | WO | disclosed |