Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19828091 | 0.81 | MAOB (0.41) | SLC6A2SLC6A4CYP2D6SLC6A3 | |
| Hydrochloric Acid SCHEMBL29960736 | 0.80 | HTR2A (0.47) | SLC6A2SLC6A4HTR2AHRH1CYP2D6 | |
| SCHEMBL8367488 | 0.79 | HTR2A (0.34) | SLC6A2SLC6A4HTR2AHRH1CYP2D6 | |
| SCHEMBL10468985 | 0.77 | HTR1A (0.47) | CYP2D6HTR1A | |
| Hydrochloric Acid SCHEMBL29960694 | 0.77 | HTR2C (0.38) | SLC6A2SLC6A4HTR2AHRH1CYP2D6 | |
| SCHEMBL19830031 | 0.76 | SIGMAR1 (0.43) | SLC6A2SLC6A4HTR2AHRH1SIGMAR1 | |
| SCHEMBL19827902 | 0.76 | SIGMAR1 (0.43) | SLC6A2SLC6A4HTR2AHRH1SIGMAR1 | |
| SCHEMBL19830010 | 0.76 | SIGMAR1 (0.43) | SLC6A2SLC6A4HTR2AHRH1SIGMAR1 | |
| SCHEMBL7950524 | 0.73 | MTNR1A (0.33) | HTR2AHRH1 | |
| SCHEMBL19827899 | 0.72 | HTR1A (0.40) | POLBESR2SLC6A2SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018023070-A1 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SUNOVION PHARMACEUTICALS, INC. (US) | 2018-02-01 | — | — | WO | disclosed |