Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 17/20 | 1.00 |
| ▸ | NPC1 | O15118 | 16/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | TP53 | P04637 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | PKM | P14618 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 4/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.74 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.74 |
| ▸ | RELA | Q04206 | 1/20 | 0.74 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5866982 | 0.85 | NPC1 (1.00) | RAB9ANPC1MEN1KMT2ATP53 | |
| SCHEMBL17712427 | 0.81 | KMT2A (0.71) | RAB9ANPC1MEN1KMT2ATP53 | |
| SCHEMBL7567703 | 0.78 | NPC1 (0.80) | RAB9ANPC1MEN1KMT2ATP53 | |
| SCHEMBL30013277 | 0.78 | RAB9A (0.63) | RAB9ANPC1MEN1KMT2ATP53 | |
| SCHEMBL6506633 | 0.78 | RAB9A (0.74) | RAB9ANPC1MEN1KMT2ATP53 | |
| SCHEMBL13779310 | 0.77 | NPC1 (1.00) | RAB9ANPC1MEN1KMT2ATP53 | |
| SCHEMBL3618549 | 0.77 | NPC1 (0.78) | RAB9ANPC1MEN1KMT2ATP53 | |
| SCHEMBL2610072 | 0.77 | NPC1 (0.78) | RAB9ANPC1MEN1KMT2ATP53 | |
| SCHEMBL7451695 | 0.77 | RAB9A (0.74) | RAB9ANPC1MEN1KMT2ATP53 | |
| SCHEMBL29013034 | 0.77 | NPC1 (1.00) | RAB9ANPC1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018019987-A1 | COMPOUNDS FOR TREATING CONGENITAL DISORDERS OF GLYCOSYLATION | Universidad Autónoma de Madrid (ES) | 2018-02-01 | — | — | WO | disclosed |
| EP-3275863-A1 | COMPOUNDS FOR TREATING CONGENITAL DISORDERS OF GLYCOSYLATION | Universidad Autónoma de Madrid (ES) | 2018-01-31 | — | — | EP | disclosed |