Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17974797 | 0.79 | TSHR (0.41) | TSHRIDO1MAPTALDH1A1AGXT | |
| SCHEMBL10780111 | 0.77 | SGMS2 (0.44) | TSHRIDO1MAPTSGMS2ALDH1A1 | |
| SCHEMBL19829640 | 0.76 | TSHR (0.39) | TSHRIDO1MAPTSGMS2ALDH1A1 | |
| SCHEMBL19831965 | 0.76 | TSHR (0.39) | TSHRIDO1MAPTSGMS2ALDH1A1 | |
| SCHEMBL18229697 | 0.75 | TSHR (0.38) | TSHRIDO1MAPTSGMS2ALDH1A1 | |
| SCHEMBL18229698 | 0.75 | TSHR (0.38) | TSHRIDO1MAPTALDH1A1AGXT | |
| SCHEMBL18229656 | 0.75 | ALDH1A1 (0.38) | TSHRIDO1ALDH1A1AGXTCYP2C19 | |
| SCHEMBL9025083 | 0.73 | TSHR (0.43) | TSHRIDO1MAPTSGMS2ALDH1A1 | |
| SCHEMBL17963379 | 0.73 | TSHR (0.43) | TSHRIDO1MAPTSGMS2ALDH1A1 | |
| SCHEMBL8711127 | 0.72 | TSHR (0.41) | TSHRIDO1MAPTSGMS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018019549-A1 | DIOXOLANONE INTERMEDIATE USEFUL IN THE SYNTHESIS OF HOMOHARRINGTONINE | INDENA S.P.A. (IT) | 2018-02-01 | — | — | WO | disclosed |