Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18310368 | 0.96 | RARB (0.32) | RARBRARARARGNPC1TP53 | |
| SCHEMBL19829163 | 0.96 | RARB (0.32) | RARBRARARARGNPC1TP53 | |
| SCHEMBL19829126 | 0.89 | RARB (0.38) | RARBRARARARGNPC1RAB9A | |
| SCHEMBL13002202 | 0.89 | RARB (0.33) | RARBRARARARGNPC1TP53 | |
| SCHEMBL19829223 | 0.89 | S1PR1 (0.30) | — | |
| SCHEMBL19829206 | 0.88 | S1PR1 (0.35) | RARBRARARARG | |
| SCHEMBL19829227 | 0.88 | KIF11 (0.36) | RARBRARARARG | |
| SCHEMBL19829128 | 0.88 | RARB (0.42) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL18719620 | 0.88 | RXRA (0.35) | RARBRARARARGNPC1TP53 | |
| SCHEMBL19829222 | 0.88 | S1PR1 (0.34) | RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030351-A1 | LIQUID CRYSTAL COMPOUND HAVING POLYFLUORO-2-BUTENOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2018-02-01 | — | — | US | disclosed |