SCHEMBL19829477

SCHEMBL19829477

CCCCCc1ccc(-c2ccc(-c3ccc(NC)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.54
HSD17B10 Q99714 2/20 0.54
TSHR P16473 1/20 0.54
ALDH1A1 P00352 2/20 0.53
MEN1 O00255 1/20 0.53
RARA P10276 1/20 0.53
MAPT P10636 1/20 0.53
MTOR P42345 1/20 0.53
KMT2A Q03164 1/20 0.53
ESR1 P03372 2/20 0.50
ADRA2A P08913 2/20 0.50
ADORA3 P0DMS8 2/20 0.50
TACR2 P21452 2/20 0.50
SLC6A2 P23975 2/20 0.50
SLC6A4 P31645 2/20 0.50
SLC6A3 Q01959 2/20 0.50
HRH3 Q9Y5N1 2/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
SHBG P04278 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27496644 0.94 ESR1 (0.55) HSD17B10ALDH1A1ESR1ADRA2AADORA3
SCHEMBL4083403 0.92 ESR1 (0.59) HSD17B10ALDH1A1ESR1ADRA2AADORA3
SCHEMBL30468687 0.92 ESR1 (0.59) HSD17B10ALDH1A1ESR1ADRA2AADORA3
SCHEMBL19513921 0.92 ESR1 (0.59) HSD17B10ALDH1A1ESR1ADRA2AADORA3
SCHEMBL8963454 0.92 ESR1 (0.59) HSD17B10ALDH1A1ESR1ADRA2AADORA3
SCHEMBL15766189 0.92 ESR1 (0.59) HSD17B10ALDH1A1ESR1ADRA2AADORA3
SCHEMBL4093509 0.92 ESR1 (0.59) HSD17B10ALDH1A1ESR1ADRA2AADORA3
SCHEMBL177483 0.92 ESR1 (0.59) HSD17B10ALDH1A1ESR1ADRA2AADORA3
SCHEMBL4089466 0.92 ESR1 (0.59) HSD17B10ALDH1A1ESR1ADRA2AADORA3
SCHEMBL8963483 0.92 ESR1 (0.59) HSD17B10ALDH1A1ESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10167426-B2 Reactive perpendicular aligned organosilicon material and manufacture method of liquid crystal display panel SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2019-01-01 US disclosed
US-20180030353-A1 REACTIVE PERPENDICULAR ALIGNED ORGANOSILICON MATERIAL AND MANUFACTURE METHOD OF LIQUID CRYSTAL DISPLAY PANEL SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2018-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180030353-A1 REACTIVE PERPENDICULAR ALIGNED ORGANOSILICON MATERIAL AND MANUFACTURE METHOD OF LIQUID CRYSTAL DISPLAY PANEL VCL, C1S, CFH RARB 4357/4885HSD17B10 1159/4885TSHR 4651/4885
US-10167426-B2 Reactive perpendicular aligned organosilicon material and manufacture method of liquid crystal display panel VCL, C1S, CFH RARB 4357/4885HSD17B10 1159/4885TSHR 4651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.