Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | TACR2 | P21452 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SHBG | P04278 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | TST | Q16762 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28152699 | 1.00 | ESR1 (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL19513921 | 1.00 | ESR1 (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL15766189 | 1.00 | ESR1 (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL4093509 | 1.00 | ESR1 (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL8963483 | 1.00 | ESR1 (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL4083403 | 1.00 | ESR1 (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL30468687 | 1.00 | ESR1 (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL8963454 | 1.00 | ESR1 (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL4089466 | 1.00 | ESR1 (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL8963306 | 1.00 | ESR1 (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605146-B2 | Process for producing an amide compound | NIHON MEDI-PHYSICS COMPANY, LIMITED (JP) | 2009-10-20 | — | — | US | claimed |
| US-20020077456-A1 | Process for producing an amide compound | NIHON MEDI-PHYSICS COMPANY, LIMITED (JP) | 2002-06-20 | — | — | US | claimed |
| EP-1199312-A2 | Process for producing an amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-04-24 | — | — | EP | claimed |
| US-9707205-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2017-07-18 | — | — | US | disclosed |
| EP-2344484-B1 | S1P RECEPTORS MODULATORS AND USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2016-06-08 | — | — | EP | disclosed |
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD. (AU) | 2016-02-11 | — | — | US | disclosed |
| US-9193716-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2015-11-24 | — | — | US | disclosed |
| CN-103958548-A | Method for producing olefin block polymer using plurality of types of transition metal catalysts | SUMITOMO CHEMICAL CO | 2014-07-30 | — | — | CN | disclosed |
| CN-101878236-B | Ethylene-alpha-olefin copolymer and molded body | SUMITOMO CHEMICAL CO | 2014-05-07 | — | — | CN | disclosed |
| CN-103732632-A | Method for producing olefin block polymer using group 4 transition metal complex | SUMITOMO CHEMICAL CO | 2014-04-16 | — | — | CN | disclosed |
| US-8680282-B2 | Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2014-03-25 | — | — | US | disclosed |
| CN-1537873-A | Polyaddition catalyst component, polyaddition catalyst and process for preparing addition polymer | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-10-20 | — | — | CN | disclosed |
| CN-1537874-A | Polyaddition catalyst component, polyaddition catalyst and method for preparing addition polymer | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-10-20 | — | — | CN | disclosed |
| CN-1532209-A | Contact product, catalytic component and addition polymerizing cathlyst and method for producing addition polymer | 住友化学工业株式会社 | 2004-09-29 | — | — | CN | disclosed |
| CN-1530378-A | Catalyst component for polyaddition, catalyst and method for producing addition polymer | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-09-22 | — | — | CN | disclosed |
| CN-1422286-A | Modified particle, support, catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | CN | disclosed |
| CN-1408738-A | Catalytic component for addition polymerization, process for producing addition polymerization and process for producing addition polymer | SUMITOMO CHEMICAL CO (JP) | 2003-04-09 | — | — | CN | disclosed |
| US-20020077456-A1 | Process for producing an amide compound | NIHON MEDI-PHYSICS COMPANY, LIMITED (JP) | 2002-06-20 | — | — | US | disclosed |
| EP-1199312-A2 | Process for producing an amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-04-24 | — | — | EP | disclosed |
| CN-1306011-A | Polyaddition catalyst component, polyaddition catalyst and method for preparing addition polymer | SUMITOMO CHEMICAL CO (JP) | 2001-08-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | S1PR1, S1PR5, S1PR2 | ESR1 1797/4885ADRA2A 280/4885ADORA3 305/4885 |
| US-20020077456-A1 | Process for producing an amide compound | NAAA, ACMSD, CPS1 | ESR1 4665/4885ADRA2A 3641/4885ADORA3 3233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.