SCHEMBL4083403

SCHEMBL4083403

CCCCCCc1ccc(NC)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.59
ADRA2A P08913 2/20 0.59
ADORA3 P0DMS8 2/20 0.59
TACR2 P21452 2/20 0.59
SLC6A2 P23975 2/20 0.59
SLC6A4 P31645 2/20 0.59
SLC6A3 Q01959 2/20 0.59
KDM4E B2RXH2 1/20 0.59
ALDH1A1 P00352 1/20 0.59
LMNA P02545 1/20 0.59
SHBG P04278 1/20 0.59
TP53 P04637 1/20 0.59
CYP3A4 P08684 1/20 0.59
HSPD1 P10809 1/20 0.59
ADRB3 P13945 1/20 0.59
HTR2C P28335 1/20 0.59
HSPE1 P61604 1/20 0.59
HIF1A Q16665 1/20 0.59
TST Q16762 1/20 0.59
HSD17B10 Q99714 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28152699 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL177483 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL19513921 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL15766189 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL4093509 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL8963483 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL30468687 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL8963454 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL4089466 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL8963306 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167104-A1 NEW IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1 AND/OR CLK4 PERHA PHARMACEUTICALS (FR) 2023-06-01 US disclosed
US-20160087219-A1 LIGHT STABILIZER, ORGANIC PHOTOVOLTAIC CELL CONTAINING THE SAME AND METHOD FOR PREPARING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-03-24 US disclosed
CN-103958548-A Method for producing olefin block polymer using plurality of types of transition metal catalysts SUMITOMO CHEMICAL CO 2014-07-30 CN disclosed
CN-101878236-B Ethylene-alpha-olefin copolymer and molded body SUMITOMO CHEMICAL CO 2014-05-07 CN disclosed
CN-103732632-A Method for producing olefin block polymer using group 4 transition metal complex SUMITOMO CHEMICAL CO 2014-04-16 CN disclosed
CN-102459365-B Ethylene/alpha-olefin copolymer and moldings SUMITOMO CHEMICAL CO 2013-08-21 CN disclosed
CN-102459436-B Resin composition for crosslinking/foam molding, crosslinked molded foam, member for footwear, and footwear SUMITOMO CO LTD 2013-07-31 CN disclosed
CN-101878237-B Ethylene-alpha-olefin copolymer and molded body SUMITOMO CO LTD 2013-04-24 CN disclosed
CN-1680394-B Process for producing compound, catalyst component, process for producing catalyst, and process for producing addition polymer SUMITOMO CO LTD 2012-11-21 CN disclosed
CN-101878235-B Ethylene-alpha-olefin copolymer and molded article SUMITOMO CO LTD 2012-08-15 CN disclosed
CN-1537872-A Polyaddition catalyst component, polyaddition catalyst, and method for preparing addition polymer ס�ѻ�ѧ��ҵ��ʽ���� 2004-10-20 CN disclosed
CN-1537874-A Polyaddition catalyst component, polyaddition catalyst and method for preparing addition polymer ס�ѻ�ѧ��ҵ��ʽ���� 2004-10-20 CN disclosed
CN-1537873-A Polyaddition catalyst component, polyaddition catalyst and process for preparing addition polymer ס�ѻ�ѧ��ҵ��ʽ���� 2004-10-20 CN disclosed
CN-1532209-A Contact product, catalytic component and addition polymerizing cathlyst and method for producing addition polymer 住友化学工业株式会社 2004-09-29 CN disclosed
CN-1530378-A Catalyst component for polyaddition, catalyst and method for producing addition polymer ס�ѻ�ѧ��ҵ��ʽ���� 2004-09-22 CN disclosed
CN-1422286-A Modified particle, support, catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL CO (JP) 2003-06-04 CN disclosed
CN-1408738-A Catalytic component for addition polymerization, process for producing addition polymerization and process for producing addition polymer SUMITOMO CHEMICAL CO (JP) 2003-04-09 CN disclosed
CN-1306011-A Polyaddition catalyst component, polyaddition catalyst and method for preparing addition polymer SUMITOMO CHEMICAL CO (JP) 2001-08-01 CN disclosed
US-4251667-A Process for the preparation of aromatic urethanes ATLANTIC RICHFIELD COMPANY (US) 1981-02-17 US disclosed
US-4222959-A Process for the preparation of aromatic formamides ATLANTIC RICHFIELD COMPANY (US) 1980-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160087219-A1 LIGHT STABILIZER, ORGANIC PHOTOVOLTAIC CELL CONTAINING THE SAME AND METHOD FOR PREPARING THE SAME OR10J3, SOAT1, SOAT2 ESR1 2481/4885ADRA2A 4438/4885ADORA3 4707/4885
US-20230167104-A1 NEW IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1 AND/OR CLK4 CLK1, CLK2, CLK3 ESR1 4334/4885ADRA2A 2794/4885ADORA3 1480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.