Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B17 | O75795 | 2/20 | 0.40 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.30 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19827777 | 1.00 | UGT2B17 (0.40) | UGT2B17HSPA1APTPN7ALDH1A1TSHR | |
| SCHEMBL19829927 | 1.00 | UGT2B17 (0.40) | UGT2B17HSPA1APTPN7ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL19810426 | 0.98 | UGT2B17 (0.39) | UGT2B17ALDH1A1 | |
| SCHEMBL19827775 | 0.82 | HTR2A (0.31) | — | |
| Hydrochloric Acid SCHEMBL19810446 | 0.81 | HTR2A (0.32) | — | |
| SCHEMBL19827773 | 0.79 | UGT2B17 (0.41) | UGT2B17HSPA1APTPN7 | |
| SCHEMBL19829969 | 0.74 | AADAT (0.38) | ALDH1A1 | |
| SCHEMBL19827813 | 0.74 | AADAT (0.38) | ALDH1A1 | |
| SCHEMBL19829929 | 0.74 | AADAT (0.38) | ALDH1A1 | |
| SCHEMBL13114074 | 0.73 | UGT2B17 (0.55) | UGT2B17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180028492-A1 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | PGI DRUG DISCOVERY LLC | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180028492-A1 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | ACHE, CHAT, MAOB | UGT2B17 237/4885HSPA1A 3449/4885PTPN7 3598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.