Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | UBE2M | P61081 | 4/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL842801 | 0.99 | GALR3 (0.39) | GALR3RAB9AKCNH2GPR119LMNA | |
| SCHEMBL1979921 | 0.93 | GALR3 (0.36) | GALR3RAB9AKCNH2GPR119LMNA | |
| Hydrochloric Acid SCHEMBL842536 | 0.92 | GALR3 (0.36) | GALR3RAB9AKCNH2GPR119LMNA | |
| SCHEMBL1981132 | 0.92 | KCNH2 (0.37) | GALR3RAB9AKCNH2GPR119LMNA | |
| Hydrochloric Acid SCHEMBL842999 | 0.92 | MCHR1 (0.37) | GALR3RAB9AKCNH2GPR119LMNA | |
| SCHEMBL1982919 | 0.91 | KCNH2 (0.39) | GALR3RAB9AKCNH2GPR119UBE2M | |
| Hydrochloric Acid SCHEMBL843150 | 0.90 | KCNH2 (0.38) | GALR3RAB9AKCNH2GPR119UBE2M | |
| SCHEMBL1981620 | 0.90 | GALR3 (0.44) | GALR3RAB9ALMNAQPCTUBE2M | |
| SCHEMBL842802 | 0.89 | KCNH2 (0.39) | GALR3RAB9AKCNH2GPR119UBE2M | |
| Hydrochloric Acid SCHEMBL842751 | 0.89 | GALR3 (0.43) | GALR3RAB9ALMNAQPCTUBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410276-B2 | Nitrogenous heterocyclic derivative and medicine containing the same as an active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-04-02 | — | — | US | claimed |
| US-20110152520-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVE AND MEDICINE CONTAINING THE SAME AS AN ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-06-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152520-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVE AND MEDICINE CONTAINING THE SAME AS AN ACTIVE INGREDIENT | CXCR3, CCR5, CCR1 | GALR3 650/4885RAB9A 953/4885KCNH2 4002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.