SCHEMBL1983015

SCHEMBL1983015

Cc1ccccc1NCCCO

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.69
HTT P42858 2/20 0.69
ALDH1A1 P00352 5/20 0.51
HPGD P15428 3/20 0.51
GAA P10253 2/20 0.51
KDM4E B2RXH2 2/20 0.51
TSHR P16473 1/20 0.51
HSD17B10 Q99714 1/20 0.51
BRD4 O60885 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ADRA2C P18825 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
POLB P06746 1/20 0.43
RAD52 P43351 1/20 0.43
CYP19A1 P11511 1/20 0.42
GLA P06280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12330516 0.94 MAPT (0.67) MAPTHTTALDH1A1HPGDGAA
SCHEMBL29589735 0.88 MAPT (0.75) MAPTHTTALDH1A1HPGDGAA
SCHEMBL56497 0.88 MAPT (0.75) MAPTHTTALDH1A1HPGDGAA
SCHEMBL26928986 0.85 KMT2A (0.53) MAPTHTTALDH1A1HPGDGAA
SCHEMBL76608 0.83 MAPT (1.00) MAPTHTTALDH1A1HPGDGAA
SCHEMBL29379717 0.83 MAPT (1.00) MAPTHTTALDH1A1HPGDGAA
SCHEMBL6255036 0.82 BRD4 (0.49) MAPTHTTALDH1A1HPGDGAA
SCHEMBL4603846 0.82 ALDH1A1 (0.53) MAPTHTTALDH1A1HPGDGAA
SCHEMBL1485755 0.82 HTT (0.72) MAPTHTTALDH1A1HPGDGAA
SCHEMBL14095072 0.81 MAPT (0.64) MAPTHTTALDH1A1GAABRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023140640-A1 HETEROARYL DERIVATIVE AND USES THEREOF 한양대학교 산학협력단 2023-07-27 WO disclosed
US-10941229-B2 Bridged anilinyl phenyl phenol catalyst compounds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-03-09 US disclosed
US-10941229-B2 Bridged anilinyl phenyl phenol catalyst compounds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-03-09 US disclosed
US-20200095352-A1 Bridged Anilinyl Phenyl Phenol Catalyst Compounds EXXONMOBIL CHEMICAL PATENTS INC. 2020-03-26 US disclosed
US-9492989-B2 Composition and method for manufacture of a fibrous polyurethane composite product HAUPT ROBERT A (US) 2016-11-15 US disclosed
US-8865287-B2 Rapid curing aldehyde resin-polyisocyanate composition and method for producing hybrid polymer RAMBUS INC. 2014-10-21 US disclosed
EP-2352773-A1 RAPID CURING ALDEHYDE RESIN-POLYISOCYANATE COMPOSITION AND METHOD FOR PRODUCING HYBRID POLYMER Sylvanova, Inc. (US) 2011-08-10 EP disclosed
US-20110189490-A1 COMPOSITION AND METHOD FOR MANUFACTURE OF A FIBROUS POLYURETHANE COMPOSITE PRODUCT HAUPT ROBERT A 2011-08-04 US disclosed
US-20110151180-A1 RAPID CURING ALDEHYDE RESIN-POLYISOCYANATE COMPOSITION AND METHOD FOR PRODUCING HYBRID POLYMER RAMBUS INC. 2011-06-23 US disclosed
WO-2010019671-A1 COMPOSITION AND METHOD FOR MANUFACTURE OF A FIBROUS POLYURETHANE COMPOSITE PRODUCT SYLVANOVA, INC. (US) 2010-02-18 WO disclosed
US-4625008-A Adhesives which contain acrylic acid derivatives of 5,6-dihydro-dicyclopentadienol BAYER AKTIENGESELLSCHAFT (DE) 1986-11-25 US disclosed
EP-0197419-A2 Adhesives containing acrylic derivatives of 5,6-dihydro-di-cyclopentadienol BAYER AG (DE) 1986-10-15 EP disclosed
EP-0058868-B1 DERIVATIVES OF TETRAHYDROPYRIMIDINON, PROCESS FOR THEIR PREPARATION AND HERBICIDES CONTAINING THOSE DERIVATIVES AS ACTIVE PRODUCTS NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1984-04-11 EP disclosed
US-4402731-A Herbicidally active novel substituted tetrahydropyrimidinones NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1983-09-06 US disclosed
EP-0058868-A1 Derivatives of tetrahydropyrimidinon, process for their preparation and herbicides containing those derivatives as active products NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1982-09-01 EP disclosed
US-4340681-A Process for the manufacture of foamed or non-foamed compositions REUTER TECHNOLOGIE GMBH (DE) 1982-07-20 US disclosed
WO-1980000705-A1 PROCESS FOR PREPARING FOAMING OR NON FOAMING MASSES BISCHOFSHEIM CHEMIE ANLAGEN (DE) 1980-04-17 WO disclosed
WO-1979000161-A1 PROCESS FOR PREPARING MATERIALS IN FORM OF FOAM OR NOT REUTER TECHNOLOGIE GMBH (DE) 1979-04-05 WO disclosed
US-4123599-A PHENOLIC RESINS REACTED WITH ORGANIC DIISOCYANATES AND/OR POLYISOCYANTES IN THE PRESENCE OF METAL POWDERS AND/OR METAL OXIDE POWDERS CHEMIE-ANLAGENBAU BISCHOFSHEIM GMBH (DE) 1978-10-31 US disclosed
US-4098730-A Non-flammable organo-red mud polymers, some of which are electrically conductive, and process for their manufacture METALLGESELLSCHAFT AKTIENGESELLSCHAFT (DE) 1978-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200095352-A1 Bridged Anilinyl Phenyl Phenol Catalyst Compounds METTL3, SETD7, PUF60 MAPT 2041/4885HTT 1280/4885ALDH1A1 2464/4885
US-10941229-B2 Bridged anilinyl phenyl phenol catalyst compounds METTL3, SETD7, PUF60 MAPT 2041/4885HTT 1280/4885ALDH1A1 2464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.