Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | USP14 | P54578 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831033 | 0.90 | MAPK8 (0.45) | MAPK8USP14PPARGMAPK9 | |
| SCHEMBL19831040 | 0.87 | MAPK8 (0.52) | MAPK8HPGDMAPTRAB9AUSP14 | |
| SCHEMBL19831088 | 0.85 | ENPP2 (0.48) | MAPK8MAPTPPARGMAPK9MEN1 | |
| SCHEMBL19831224 | 0.84 | MAPK8 (0.48) | MAPK8PPARGPOLBKDM4EMEN1 | |
| SCHEMBL19831116 | 0.82 | MAPK8 (0.45) | MAPK8USP14PPARGMAPK9 | |
| SCHEMBL19831198 | 0.82 | PPARG (0.48) | MAPK8HPGDMAPTRAB9APPARG | |
| SCHEMBL19831112 | 0.81 | MAPK8 (0.42) | MAPK8USP14PPARGMAPK9 | |
| SCHEMBL19831032 | 0.79 | MAPK1 (0.52) | MAPK8HPGDUSP14KDM4EMAPK9 | |
| SCHEMBL19831246 | 0.79 | MAPK8 (0.41) | MAPK8USP14PPARGMAPK9 | |
| SCHEMBL19831090 | 0.78 | SMN1; SMN2 (0.46) | MAPK8PPARGPOLBMAPK9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018021762-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 현대약품 주식회사 | 2018-02-01 | — | — | WO | disclosed |