SCHEMBL19831745

SCHEMBL19831745

COCc1ccc(C(c2ccc(COC)cc2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 1/20 0.50
▸ ESR2 Q92731 1/20 0.50
▸ IDO1 P14902 2/20 0.44
▸ KMT2A Q03164 1/20 0.38
▸ PDK2 Q15119 1/20 0.37
▸ MAOB P27338 5/20 0.37
▸ PTPN1 P18031 4/20 0.35
▸ PTPN2 P17706 3/20 0.35
▸ PTPN6 P29350 3/20 0.35
▸ PTPRC P08575 2/20 0.35
▸ PTPRB P23467 2/20 0.35
▸ PTPN11 Q06124 2/20 0.35
▸ CDC25A P30304 1/20 0.35
▸ ERN1 O75460 1/20 0.33
▸ APP P05067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19425945 0.87 IDO1 (0.45) ESR1ESR2IDO1PDK2MAOB
SCHEMBL791859 0.83 IDO1 (0.63) IDO1KMT2AMAOB
SCHEMBL11308991 0.78 APP (0.41) ESR1ESR2IDO1KMT2APDK2
SCHEMBL20999104 0.77 IDO1 (0.50) IDO1PDK2MAOB
SCHEMBL134443 0.76 IDO1 (0.46) IDO1MAOBERN1APP
SCHEMBL10601214 0.76 ESR1 (0.48) ESR1ESR2IDO1KMT2AAPP
SCHEMBL12191287 0.76 ESR1 (0.50) ESR1ESR2KMT2A
SCHEMBL780050 0.76 APP (0.53) KMT2AAPP
SCHEMBL10357375 0.72 RORC (0.39) ESR1ESR2IDO1KMT2APDK2
SCHEMBL20892298 0.72 APP (0.38) ESR1ESR2IDO1KMT2APDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357535-A1 CROSSLINKABLE ELASTOMER COMPOSITION AND FLUORORUBBER MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2023-11-09 — — US disclosed
US-20230303732-A1 METHOD FOR MANUFACTURING PERFLUOROELASTOMER AQUEOUS DISPERSION, COMPOSITION, CROSSLINKABLE COMPOSITION, AND CROSSLINKED PRODUCT DAIKIN INDUSTRIES, LTD. (JP) 2023-09-28 — — US disclosed
US-11655339-B2 Polybenzimidazole, precursor polyamide thereof, and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-23 — — US disclosed
US-20230128992-A1 POLYBENZIMIDAZOLE, PRECURSOR POLYAMIDE THEREOF, AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-04-27 — — US disclosed
US-11548983-B2 Polybenzimidazole, precursor polyamide thereof, and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-01-10 — — US disclosed
US-20220204658-A1 METHOD FOR PRODUCING PERFLUOROELASTOMER AND COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2022-06-30 — — US disclosed
US-20220073722-A1 COMPOSITION AND MOLDED ARTICLE AKITA UNIVERSITY (JP) 2022-03-10 — — US disclosed
US-20210317295-A1 COMPOSITION AND MOLDED ARTICLE CONTAINING FLUORINE-CONTAINING POLYMER DAIKIN INDUSTRIES, LTD. (JP) 2021-10-14 — — US disclosed
US-11072700-B2 Composition comprising fluoropolymer and molded article DAIKIN INDUSTRIES, LTD. (JP) 2021-07-27 — — US disclosed
US-20210179804-A1 Fluorine-Containing Elastomer Compositions Including Microdiamond GREENE, TWEED TECHNOLOGIES, INC. 2021-06-17 — — US disclosed
US-20200291181-A1 POLYBENZIMIDAZOLE, PRECURSOR POLYAMIDE THEREOF, AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2020-09-17 — — US disclosed
US-10745524-B2 Fluorine-containing and silicon containing compound OCHANOMIZU UNIVERSITY (JP) 2020-08-18 — — US disclosed
EP-3666814-A1 POLYBENZIMIDAZOLE, PRECURSOR POLYAMIDE THEREOF, AND METHOD FOR PRODUCING SAME Daikin Industries, Ltd. (JP) 2020-06-17 — — EP disclosed
US-20200181386-A1 FLUOROELASTOMER COMPOSITION AND MOLDED ARTICLE THEREOF TOKYO INSTITUTE OF TECHNOLOGY (JP) 2020-06-11 — — US disclosed
EP-3636711-A1 FLUOROELASTOMER COMPOSITION AND MOLDED ARTICLE THEREOF Tokyo Institute of Technology (JP) 2020-04-15 — — EP disclosed
US-10377881-B2 Composition and molded article AKITA UNIVERSITY (JP) 2019-08-13 — — US disclosed
US-20190169415-A1 COMPOSITION AND MOLDED ARTICLE AKITA UNIVERSITY (JP) 2019-06-06 — — US disclosed
US-20190023851-A1 FLUORINE-CONTAINING AND SILICON-CONTAINING COMPOUND OCHANOMIZU UNIVERSITY (JP) 2019-01-24 — — US disclosed
US-20180179374-A1 COMPOSITION COMPRISING FLUOROPOLYMER AND MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2018-06-28 — — US disclosed
US-20180030246-A1 COMPOSITION AND MOLDED ARTICLE AKITA UNIVERSITY (JP) 2018-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10745524-B2 Fluorine-containing and silicon containing compound FEM1B, CCNT2, AFF2 ESR1 399/4885ESR2 618/4885IDO1 2069/4885
US-20190023851-A1 FLUORINE-CONTAINING AND SILICON-CONTAINING COMPOUND FEM1B, CCNT2, CCNB2 ESR1 542/4885ESR2 517/4885IDO1 2101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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