SCHEMBL198318

SCHEMBL198318

Cc1ccc(S(=O)(=O)NCc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 1.00
CA9 Q16790 2/20 1.00
CYP1A2 P05177 2/20 1.00
CYP3A4 P08684 2/20 1.00
ATM Q13315 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
CYP19A1 P11511 1/20 0.78
KEAP1 Q14145 1/20 0.76
LMNA P02545 3/20 0.71
SMN1; SMN2 Q16637 2/20 0.71
HTT P42858 1/20 0.71
ALDH1A1 P00352 5/20 0.69
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
MAPT P10636 2/20 0.64
GAA P10253 1/20 0.64
HPGD P15428 1/20 0.64
CNR2 P34972 1/20 0.63
CA1 P00915 1/20 0.63
CA2 P00918 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28676437 0.98 CA12 (0.97) CA12CA9CYP1A2CYP3A4ATM
SCHEMBL4662819 0.93 CA12 (0.87) CA12CA9CYP1A2CYP3A4ATM
SCHEMBL25547142 0.91 CA12 (0.83) CA12CA9CYP1A2CYP3A4ATM
SCHEMBL29019313 0.90 CA12 (0.82) CA12CA9CYP1A2CYP3A4ATM
SCHEMBL407414 0.87 KEAP1 (1.00) CA12CA9CYP1A2CYP3A4ATM
SCHEMBL12793673 0.86 KEAP1 (0.76) CA12CA9CYP1A2CYP3A4ATM
SCHEMBL17168318 0.85 CA12 (0.74) CA12CA9CYP1A2CYP3A4ATM
Hydrochloric Acid SCHEMBL3516799 0.85 KEAP1 (0.96) CA12CA9CYP1A2CYP3A4ATM
SCHEMBL29694137 0.84 KEAP1 (0.73) CA12CA9CYP1A2CYP3A4ATM
SCHEMBL17827613 0.84 CA12 (0.73) CA12CA9CYP1A2CYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 377 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745119-A1 ISOCYANATE COMPOSITION Hanwha Solutions Corporation (KR) 2026-05-20 EP claimed
EP-4482481-B1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES SOM INNOVATION BIOTECH S A (ES) 2025-11-12 EP claimed
US-20250152567-A1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES REGENTS OF THE UNIVERSITY OF MINNESOTA 2025-05-15 US claimed
WO-2025042219-A1 ISOCYANATE COMPOSITION 한화솔루션 주식회사 2025-02-27 WO claimed
EP-4482481-A1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES Som Innovation Biotech, S.L. (ES) 2025-01-01 EP claimed
CN-118993622-A Thermal insulation material for non-bearing enclosure partition wall and preparation method thereof 北京工业大学 2024-11-22 CN claimed
CN-118973560-A Compounds for the treatment of dystrophin 索姆创新生物技术公司 2024-11-15 CN claimed
CN-118434410-A Recovery of giant organelles and uses thereof 巴黎科学与文学联大 2024-08-02 CN claimed
WO-2023156645-A1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES SOM INNOVATION BIOTECH, S.A. (ES) 2023-08-24 WO claimed
EP-4230196-A1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES Som Innovation Biotech, S.A. (ES) 2023-08-23 EP claimed
US-20060199728-A1 Enantioselective amination and etherification YALE UNIVERSITY (US) 2006-09-07 US claimed
WO-2004024684-A2 ENANTIOSELECTIVE AMINATION AND ETHERIFICATION YALE UNIVERSITY (US) 2004-03-25 WO claimed
EP-0215898-B1 LIQUID MEMBRANE SYSTEM FOR THE REMOVAL OF NITRATE FROM WATER THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1990-12-19 EP claimed
US-4929530-A OXIDATIVE LEUCO DYES, PHOTO-OXIDIZERS, REDUCING AGENTS, ORGANIC SULFONAMIDES AND PHENOLIC COMPONENTS; EXPOSING TO LIGHT FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US claimed
EP-0215898-A4 LIQUID MEMBRANE SYSTEM FOR THE REMOVAL OF NITRATE FROM WATER. UNIV MINNESOTA (US) 1988-06-20 EP claimed
US-4737309-A QUATERNARY MAMONIUM SALT COMPLEXING AGENTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1988-04-12 US claimed
US-4661257-A QUATERNARY AMMONIUM SALTS AS COMPLEXING AGENTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1987-04-28 US claimed
EP-0215898-A1 LIQUID MEMBRANE SYSTEM FOR THE REMOVAL OF NITRATE FROM WATER. UNIV MINNESOTA (US) 1987-04-01 EP claimed
WO-1986005477-A1 LIQUID MEMBRANE SYSTEM FOR THE REMOVAL OF NITRATE FROM WATER REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1986-09-25 WO claimed
US-4400509-A WITH HEXAMETHYLDISILANE WITH AN ORGANONITROGEN CATALYST GIST-BROCADES N.V. (NL) 1983-08-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250152567-A1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES MTPN, UTRN, TTN CA12 2468/4885CA9 2039/4885CYP1A2 4005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.