Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.69 |
| ▸ | PKLR | P30613 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31315853 | 0.82 | PKM (1.00) | PKMPKLRNPC1RAB9AHTT | |
| SCHEMBL1722721 | 0.82 | PKM (1.00) | PKMPKLRNPC1RAB9AHTT | |
| SCHEMBL17102104 | 0.81 | PKM (0.71) | PKMPKLRNPC1RAB9AHTT | |
| SCHEMBL1044915 | 0.79 | HTT (0.96) | PKMPKLRNPC1RAB9AHTT | |
| SCHEMBL17102055 | 0.79 | GAA (0.61) | PKMPKLRNPC1RAB9AHTT | |
| SCHEMBL18383554 | 0.79 | GAA (0.61) | PKMPKLRNPC1RAB9AHTT | |
| SCHEMBL17100585 | 0.78 | PKM (0.67) | PKMPKLRNPC1RAB9AHTT | |
| SCHEMBL4555472 | 0.78 | HTT (1.00) | PKMPKLRNPC1RAB9AHTT | |
| SCHEMBL8508293 | 0.78 | HTT (1.00) | PKMPKLRNPC1RAB9AHTT | |
| SCHEMBL11888962 | 0.77 | PKM (0.65) | PKMPKLRNPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119782-B1 | 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS | REMYND NV (BE) | 2018-01-31 | — | — | EP | disclosed |