Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19719633 | 0.88 | KDM4E (0.42) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL19719507 | 0.86 | ALDH1A1 (0.46) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL19833478 | 0.85 | PIK3CD (0.42) | LSS | |
| SCHEMBL15472156 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HPGDDUSP3PTPN7KDM4E | |
| SCHEMBL14900587 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HPGDDUSP3PTPN7KDM4E | |
| SCHEMBL14889819 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HPGDDUSP3PTPN7KDM4E | |
| SCHEMBL14889820 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HPGDDUSP3PTPN7KDM4E | |
| SCHEMBL19833596 | 0.85 | NAAA (0.44) | ALDH1A1HPGDDUSP3PTPN7KDM4E | |
| SCHEMBL19719509 | 0.84 | KDM4E (0.44) | ALDH1A1HPGDMAPTDUSP3PTPN7 | |
| SCHEMBL19834161 | 0.84 | KDM4E (0.44) | ALDH1A1HPGDMAPTDUSP3PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3275448-A1 | NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES | Kyowa Hakko Kirin Co., Ltd. (JP) | 2018-01-31 | — | — | EP | disclosed |