Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.44 |
| ▸ | HTR1D | P28221 | 7/20 | 0.41 |
| ▸ | HTR1A | P08908 | 6/20 | 0.41 |
| ▸ | HTR1B | P28222 | 6/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19834158 | 0.93 | MGLL (0.48) | MGLLNR3C2HTR1DHTR1AHTR1B | |
| SCHEMBL19834075 | 0.92 | MGLL (0.51) | MGLLHTR1DHTR1AHTR1BADRB1 | |
| SCHEMBL19834017 | 0.91 | MGLL (0.54) | MGLLNR3C2HTR1DHTR1AHTR1B | |
| SCHEMBL19833794 | 0.90 | MGLL (0.67) | MGLLNR3C2 | |
| SCHEMBL19834118 | 0.89 | MGLL (0.49) | MGLLNR3C2HTR1DHTR1AHTR1B | |
| SCHEMBL19833877 | 0.89 | MGLL (0.59) | MGLLNR3C2NR3C1PGR | |
| SCHEMBL19834063 | 0.87 | MGLL (0.48) | MGLLHTR1DHTR1AHTR1BADRB1 | |
| SCHEMBL19833716 | 0.87 | MGLL (0.48) | MGLLHTR1DHTR1AHTR1BADRB1 | |
| SCHEMBL19833712 | 0.86 | MGLL (0.65) | MGLLNR3C2NR3C1PGR | |
| SCHEMBL19834079 | 0.86 | MGLL (0.57) | MGLLHTR1DHTR1AHTR1BADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279191-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2020-09-02 | — | — | EP | disclosed |
| US-10106556-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-10-23 | — | — | US | disclosed |
| US-20180079756-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-22 | — | — | US | disclosed |
| US-20180079756-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-22 | — | — | US | disclosed |
| EP-3279191-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-07 | — | — | EP | disclosed |
| EP-3279191-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079756-A1 | HETEROCYCLIC COMPOUND | MAG, ACHE, HTT | MGLL 129/4885NR3C2 2434/4885HTR1D 567/4885 |
| US-10106556-B2 | Heterocyclic compound | MAG, ACHE, HTT | MGLL 129/4885NR3C2 2434/4885HTR1D 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.