Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775887 | 0.77 | PSIP1 (0.50) | PSIP1HSD11B1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL778104 | 0.77 | PSIP1 (0.54) | PSIP1HSD11B1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL5210088 | 0.74 | HSD11B1 (0.49) | PSIP1HSD11B1ALDH1A1MMP1MMP2 | |
| SCHEMBL19248406 | 0.73 | PSIP1 (0.56) | PSIP1HSD11B1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL1540327 | 0.73 | PSIP1 (0.56) | PSIP1HSD11B1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL7348328 | 0.73 | HSD11B1 (0.56) | PSIP1HSD11B1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL1527680 | 0.73 | HSD11B1 (0.56) | PSIP1HSD11B1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL19239760 | 0.70 | PSIP1 (0.52) | PSIP1HSD11B1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL7967868 | 0.70 | PSIP1 (0.56) | PSIP1HSD11B1ALDH1A1MMP2MMP13 | |
| SCHEMBL9499219 | 0.69 | CYP2C19 (0.58) | PSIP1HSD11B1ALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3045450-B1 | INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2018-02-07 | — | — | EP | disclosed |