SCHEMBL19835264

SCHEMBL19835264

CCCCCCCC/C=C\CCCCCCCC(=O)OCCN(CCCO)CCOC(=O)CCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.60
DNM1 Q05193 1/20 0.56
EPHX2 P34913 1/20 0.55
DGKA P23743 2/20 0.54
CNR2 P34972 2/20 0.52
ALDH1A1 P00352 1/20 0.52
MAPT P10636 1/20 0.52
THRB P10828 1/20 0.52
CNR1 P21554 1/20 0.52
PRKCA P17252 2/20 0.52
PRKCE Q02156 1/20 0.52
PRKCQ Q04759 1/20 0.52
PRKCD Q05655 1/20 0.52
FAAH O00519 1/20 0.49
TRPV1 Q8NER1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28424646 0.93 MGLL (0.62) MGLLDNM1EPHX2DGKACNR2
SCHEMBL4340654 0.93 MGLL (0.62) MGLLDNM1EPHX2DGKACNR2
SCHEMBL9717060 0.93 DNM1 (0.64) MGLLDNM1EPHX2DGKAALDH1A1
SCHEMBL9717053 0.93 DNM1 (0.64) MGLLDNM1EPHX2DGKAALDH1A1
Hydrochloric Acid SCHEMBL5868518 0.92 MGLL (0.60) MGLLDNM1EPHX2DGKACNR2
Hydrochloric Acid SCHEMBL5868526 0.92 MGLL (0.60) MGLLDNM1EPHX2DGKACNR2
SCHEMBL17401269 0.92 DNM1 (0.62) MGLLDNM1EPHX2DGKAALDH1A1
SCHEMBL17411411 0.92 DNM1 (0.62) MGLLDNM1EPHX2DGKAALDH1A1
SCHEMBL24485780 0.90 MGLL (0.66) MGLLEPHX2DGKACNR2ALDH1A1
SCHEMBL15939615 0.89 MGLL (0.60) MGLLDNM1EPHX2DGKACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9920028-B2 Cationic lipid KYOWA HAKKO KIRIN CO., LTD. (JP) 2018-03-20 US disclosed
EP-3275448-A1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES Kyowa Hakko Kirin Co., Ltd. (JP) 2018-01-31 EP disclosed