Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | CNR2 | P34972 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1987824 | 0.92 | KMT2A (0.40) | CNR1CNR2KMT2APTGS2PTGS1 | |
| SCHEMBL1985253 | 0.91 | CNR1 (0.38) | CNR1CNR2KMT2APTGS2PTGS1 | |
| SCHEMBL1988695 | 0.89 | CNR1 (0.45) | CNR1CNR2KMT2APTGS2PTGS1 | |
| SCHEMBL1985967 | 0.85 | CNR1 (0.60) | CNR1CNR2 | |
| SCHEMBL1986855 | 0.85 | CNR1 (0.41) | CNR1CNR2KMT2APTGS2PTGS1 | |
| SCHEMBL1984227 | 0.84 | KMT2A (0.36) | KMT2APTGS2PTGS1LMNAPPARA | |
| SCHEMBL1983548 | 0.83 | CNR1 (0.52) | CNR1CNR2KMT2APTGS2PTGS1 | |
| SCHEMBL1989244 | 0.82 | KMT2A (0.37) | KMT2APTGS2PTGS1LMNAPPARA | |
| SCHEMBL1986995 | 0.82 | KMT2A (0.35) | CNR1CNR2KMT2APTGS2PTGS1 | |
| SCHEMBL1986031 | 0.80 | PDE4D (0.41) | LMNAMAPTTP53PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602656-B1 | PYRAZOLE DERIVATIVES HAVING AFFINITY FOR CB1 AND/OR CB2 RECEPTORS | NEUROSCIENZE PHARMANESS S C A R L (IT) | 2011-06-29 | — | — | EP | claimed |