Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1984227 | 0.92 | KMT2A (0.36) | KMT2AMAPTAPPCASP1PPP1CA | |
| SCHEMBL1986995 | 0.90 | KMT2A (0.35) | KMT2AMAPTAPPCASP1PPP1CA | |
| SCHEMBL1983836 | 0.89 | PDE4D (0.38) | KMT2AMAPTAPPSMN1; SMN2LMNA | |
| SCHEMBL1986572 | 0.87 | SMN1; SMN2 (0.39) | KMT2AMAPTAPPCASP1PPP1CA | |
| SCHEMBL1989275 | 0.87 | CNR2 (0.43) | LMNA | |
| SCHEMBL1987824 | 0.85 | KMT2A (0.40) | KMT2AMAPTAPPCASP1PPP1CA | |
| SCHEMBL1987131 | 0.84 | MAPT (0.42) | KMT2AMAPTAPPCASP1PPP1CA | |
| SCHEMBL1984671 | 0.84 | RXRA (0.39) | MAPTAPPLMNATP53ALDH1A1 | |
| SCHEMBL1983550 | 0.82 | CNR1 (0.43) | KMT2AMAPTLMNATP53MEN1 | |
| SCHEMBL1988695 | 0.80 | CNR1 (0.45) | KMT2AMAPTSMN1; SMN2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602656-B1 | PYRAZOLE DERIVATIVES HAVING AFFINITY FOR CB1 AND/OR CB2 RECEPTORS | NEUROSCIENZE PHARMANESS S C A R L (IT) | 2011-06-29 | — | — | EP | claimed |