Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RPA1 | P27694 | 2/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1983550 | 0.91 | CNR1 (0.43) | CNR1CNR2PDE4DMAPTKMT2A | |
| SCHEMBL1986031 | 0.91 | PDE4D (0.41) | PDE4DMAPTALDH1A1TP53RPA1 | |
| SCHEMBL1987138 | 0.88 | TP53 (0.39) | CNR1CNR2PDE4DMAPTALDH1A1 | |
| SCHEMBL1983811 | 0.86 | MAPT (0.40) | PDE4DRXRARXRBRXRGMAPT | |
| SCHEMBL1985252 | 0.85 | TP53 (0.46) | CNR1CNR2PDE4DMAPTKMT2A | |
| SCHEMBL1984671 | 0.84 | RXRA (0.39) | PDE4DRXRARXRBRXRGMAPT | |
| SCHEMBL1987824 | 0.83 | KMT2A (0.40) | CNR1CNR2MAPTKMT2AALDH1A1 | |
| SCHEMBL1983836 | 0.81 | PDE4D (0.38) | PDE4DMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL1983924 | 0.81 | MAPT (0.36) | PDE4DRXRARXRBRXRGMAPT | |
| SCHEMBL1988695 | 0.80 | CNR1 (0.45) | CNR1CNR2PDE4DMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602656-B1 | PYRAZOLE DERIVATIVES HAVING AFFINITY FOR CB1 AND/OR CB2 RECEPTORS | NEUROSCIENZE PHARMANESS S C A R L (IT) | 2011-06-29 | — | — | EP | claimed |