Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527881 | 0.86 | NOTUM (0.70) | TDP1ATML3MBTL1MAPTLMNA | |
| SCHEMBL16975850 | 0.85 | SMN1; SMN2 (0.71) | TDP1ATML3MBTL1MAPTLMNA | |
| SCHEMBL14679168 | 0.83 | TDP1 (0.62) | TDP1ATML3MBTL1MAPTLMNA | |
| SCHEMBL11920075 | 0.83 | TDP1 (0.62) | TDP1ATML3MBTL1MAPTSIRT2 | |
| SCHEMBL11637969 | 0.83 | TDP1 (0.62) | TDP1ATML3MBTL1MAPTSIRT2 | |
| SCHEMBL95543 | 0.83 | SMN1; SMN2 (0.69) | L3MBTL1MAPTSIRT2LMNAHPGD | |
| SCHEMBL24326634 | 0.82 | TDP1 (0.69) | TDP1ATML3MBTL1MAPTSIRT2 | |
| SCHEMBL1684613 | 0.81 | TSHR (0.74) | ATML3MBTL1MAPTLMNAHDAC2 | |
| SCHEMBL3932295 | 0.81 | RAB9A (0.71) | TDP1L3MBTL1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL10053485 | 0.81 | SMN1; SMN2 (0.63) | TDP1ATML3MBTL1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3275440-B1 | NOVEL OXADIAZOLE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME | NAT CT GERIATRICS & GERONTOLOGY (JP) | 2022-05-04 | — | — | EP | disclosed |
| EP-3275440-A1 | NOVEL OXADIAZOLE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME | National Center for Geriatrics and Gerontology (JP) | 2018-01-31 | — | — | EP | disclosed |