Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18643709 | 1.00 | HTR2C (0.37) | HTR2CACHECHRNB2CHRNA4SLC6A2 | |
| SCHEMBL19827913 | 1.00 | HTR2C (0.37) | HTR2CACHECHRNB2CHRNA4SLC6A2 | |
| SCHEMBL14449346 | 0.85 | HTR2C (0.37) | HTR2CACHECHRNB2CHRNA4SLC6A2 | |
| SCHEMBL19835912 | 0.85 | HTR2C (0.37) | HTR2CACHECHRNB2CHRNA4SLC6A2 | |
| SCHEMBL19829950 | 0.82 | ACHE (0.34) | HTR2CACHECHRNB2CHRNA4SLC6A2 | |
| SCHEMBL19827831 | 0.82 | ACHE (0.34) | HTR2CACHECHRNB2CHRNA4SLC6A2 | |
| SCHEMBL19829947 | 0.82 | ACHE (0.34) | HTR2CACHECHRNB2CHRNA4SLC6A2 | |
| SCHEMBL19810366 | 0.82 | HTR1A (0.37) | HTR2CACHECHRNB2CHRNA4SLC6A2 | |
| SCHEMBL19827763 | 0.82 | ACHE (0.34) | HTR2CACHECHRNB2CHRNA4SLC6A2 | |
| SCHEMBL19828061 | 0.82 | ACHE (0.34) | HTR2CACHECHRNB2CHRNA4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11077090-B2 | Compounds and compositions and uses thereof | SUNOVION PHARMACEUTICALS INC. (MA) | 2021-08-03 | — | — | US | disclosed |
| US-20180028492-A1 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | PGI DRUG DISCOVERY LLC | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11077090-B2 | Compounds and compositions and uses thereof | ACHE, CHAT, MAOB | HTR2C 196/4885ACHE 1/4885CHRNB2 286/4885 |
| US-20180028492-A1 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | ACHE, CHAT, MAOB | HTR2C 196/4885ACHE 1/4885CHRNB2 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.