Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19836008 | 0.84 | PTGIR (0.52) | MTNR1AMTNR1B | |
| SCHEMBL8132467 | 0.82 | CHRM2 (0.60) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL8970384 | 0.80 | CHRM2 (0.60) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL9688982 | 0.78 | CHRM2 (0.59) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL12635378 | 0.78 | CHRM2 (0.62) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL12634890 | 0.77 | CHRM2 (0.60) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL19969492 | 0.77 | CYP19A1 (0.58) | CHRM2CHRM1CHRM3HTR1A | |
| SCHEMBL12671717 | 0.76 | CHRM2 (0.67) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL8890686 | 0.74 | MTNR1A (0.66) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL472446 | 0.74 | CHRM2 (0.67) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928858-B1 | METHODS OF SYNTHESIZING A PROSTACYCLIN ANALOG | CAYMAN CHEMICAL CO INC (US) | 2018-01-31 | — | — | EP | disclosed |