Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8506488 | 0.88 | ALDH1A1 (0.49) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL110446 | 0.83 | KAT2B (0.66) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL29390623 | 0.83 | KAT2B (0.66) | KMT2AMEN1GAAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL27635117 | 0.81 | KAT2B (0.67) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL27562350 | 0.80 | KMT2A (0.52) | KMT2AMEN1GAAALDH1A1MAPT | |
| Diethanolamine SCHEMBL198856 | 0.79 | KAT2B (0.60) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL27708810 | 0.78 | KAT2B (0.59) | KMT2AMEN1ALDH1A1MAPTKAT2B | |
| SCHEMBL10433483 | 0.77 | ALDH1A1 (0.63) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL5922386 | 0.77 | KAT2B (0.71) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL8893032 | 0.76 | KMT2A (0.51) | KMT2AMEN1GAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7736395-B2 | direct dyes | L'OREAL S.A. (FR) | 2010-06-15 | — | — | US | claimed |
| EP-1738800-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| EP-1738801-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| EP-0646108-B1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | OREAL (FR) | 1998-10-14 | — | — | EP | claimed |
| US-5792221-A | DYEING GRAY TO WHITE HAIR BLUE THROUGH PURPLISH-BLUE SHADES; WATER SOLUBILITY; WASH- AND COLORFASTNESS; WEATHERPROOFING; SWEAT RESISTANCE | L'OREAL (FR) | 1998-08-11 | — | — | US | claimed |
| EP-0646109-B1 | NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES | OREAL (FR) | 1997-09-03 | — | — | EP | claimed |
| EP-0673926-B1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | OREAL (FR) | 1997-04-09 | — | — | EP | claimed |
| US-5516942-A | DIRECT DYES FOR HAIR FOR YELLOW OR PURPLE | L'OREAL (FR) | 1996-05-14 | — | — | US | claimed |
| EP-0608393-B1 | HAIR DYES | WELLA AG (DE) | 1996-03-20 | — | — | EP | claimed |
| EP-0673926-A1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | L'OREAL (FR) | 1995-09-27 | — | — | EP | claimed |
| WO-1994000414-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | claimed |
| US-4975093-A | Hair dyeing compositions containing 2,6-dinitro-phenol-derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1990-12-04 | — | — | US | claimed |
| US-11896700-B2 | Process for treating keratin fibers using an anhydrous composition comprising a compound of azomethine type comprising two pyrazolopyridine units and an aqueous composition | L'OREAL (FR) | 2024-02-13 | — | — | US | disclosed |
| US-20230137804-A1 | PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION | L'OREAL (FR) | 2023-05-04 | — | — | US | disclosed |
| CN-109311879-B | Symmetrical/asymmetrical azomethine-type direct dyes comprising at least one pyrazolopyridine unit, method for dyeing | 莱雅公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-109310607-B | Use of azomethine-type compounds bearing quinoline derivative units for dyeing keratin fibres | 莱雅公司 | 2022-04-15 | — | — | CN | disclosed |
| EP-0646108-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1995-04-05 | — | — | EP | disclosed |
| WO-1994012149-A1 | ALLYLAMINO-NITROAROMATES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1994-06-09 | — | — | WO | disclosed |
| WO-1994000415-A1 | NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | disclosed |
| WO-1994000414-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11896700-B2 | Process for treating keratin fibers using an anhydrous composition comprising a compound of azomethine type comprising two pyrazolopyridine units and an aqueous composition | KRT18, DPYD, CKAP4 | KMT2A 1294/4885MEN1 2634/4885GAA 4188/4885 |
| US-20230137804-A1 | PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION | KRT18, DPYD, CKAP4 | KMT2A 1294/4885MEN1 2634/4885GAA 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.