Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198386 | 0.76 | KMT2A (0.54) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL8893645 | 0.75 | MAPT (0.49) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL10433483 | 0.73 | ALDH1A1 (0.63) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL516294 | 0.72 | KMT2A (0.61) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL733777 | 0.70 | KMT2A (0.69) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL13689727 | 0.70 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL20984065 | 0.70 | GAA (0.67) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL29740651 | 0.70 | KMT2A (0.69) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL9400705 | 0.70 | MAPT (0.50) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL12655445 | 0.70 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5685881-A | Aromatic allylaminonitro compounds, hair dye compositions containing aromatic allylaminonitio compounds, and synthetic and natural fiber dyeing process | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1997-11-11 | — | — | US | disclosed |
| EP-0671900-B1 | ALLYLAMINO-NITROAROMATES | HENKEL KGAA (DE) | 1996-08-14 | — | — | EP | disclosed |