SCHEMBL19838822

SCHEMBL19838822

Cc1ccc(CN2c3ccccc3N(C)C2c2c(C)cc(C)cc2C)cc1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.38
▸ TP53 P04637 1/20 0.38
▸ POLB P06746 2/20 0.36
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ ACHE P22303 1/20 0.34
▸ BACE1 P56817 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ HDAC6 Q9UBN7 1/20 0.34
▸ ALDH1A1 P00352 2/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ DRD4 P21917 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15320331 0.80 KDM4E (0.45) LMNAMEN1KMT2A
Iodide SCHEMBL20786989 0.78 KDM4E (0.44) LMNAMEN1KMT2A
SCHEMBL18674333 0.67 LMNA (0.49) LMNAMEN1KMT2AACHEGAA
SCHEMBL21891259 0.66 PDGFRB (0.63) LMNAMEN1KMT2AGAAALDH1A1
SCHEMBL12189952 0.66 TNF (0.45) LMNAPOLBMEN1KMT2AGAA
SCHEMBL12189977 0.64 MEN1 (0.36) MEN1KMT2AGAAALDH1A1
SCHEMBL25205805 0.63 PSMB5 (0.36) LMNAALDH1A1NPC1RAB9ASMN1; SMN2
Bromide SCHEMBL28667620 0.62 PDGFRB (0.39) LMNAMEN1KMT2AHDAC6ALDH1A1
SCHEMBL9481198 0.62 LMNA (0.60) LMNATP53POLBMEN1KMT2A
SCHEMBL28979322 0.60 BRD4 (0.50) POLBMEN1KMT2AHDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116023659-B Crosslinked hydroxide stabilized polybenzimidazolium and polyimidazolium membranes and ionomers 西蒙弗雷泽大学 2024-09-27 — — CN disclosed
CN-116023659-A Crosslinked hydroxide stabilized polybenzimidazolium and polyimidazolium membranes and ionomers 西蒙弗雷泽大学 2023-04-28 — — CN disclosed
CN-109863227-B Hydroxide-stabilized polybenzimidazolium and polyimidazolium membranes and ionomers crosslinking 西蒙弗雷泽大学 2023-01-10 — — CN disclosed
US-11230626-B2 Crosslinking of hydroxide stable, polybenzimidazoliums and polyimidazoliums membranes and ionomers SIMON FRASER UNIVERSITY (CA) 2022-01-25 — — US disclosed
EP-3494193-A1 CROSSLINKING OF HYDROXIDE STABLE, POLYBENZIMIDAZOLIUMS AND POLYIMIDAZOLIUMS MEMBRANES AND IONOMERS Simon Fraser University (CA) 2019-06-12 — — EP disclosed
US-20190169372-A1 Crosslinking of Hydroxide Stable, Polybenzimidazoliums and Polyimidazoliums Membranes and Ionomers SIMON FRASER UNIVERSITY (CA) 2019-06-06 — — US disclosed
WO-2018026743-A1 CROSSLINKING OF HYDROXIDE STABLE, POLYBENZIMIDAZOLIUMS AND POLYIMIDAZOLIUMS MEMBRANES AND IONOMERS SIMON FRASER UNIVERSITY (CA) 2018-02-08 — — WO disclosed
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