Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.85 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.62 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.62 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973476 | 0.92 | FTO (1.00) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL29815056 | 0.92 | FTO (1.00) | FTOMAPTMEN1HTTKMT2A | |
| Fluorescein SCHEMBL30668213 | 0.89 | FTO (0.79) | FTOMAPTMEN1HTTKMT2A | |
| Fluorescein SCHEMBL7713235 | 0.89 | FTO (0.79) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL14860604 | 0.87 | FTO (0.86) | FTOMAPTMEN1HTTKMT2A | |
| Fluorescein SCHEMBL17541743 | 0.81 | FTO (0.81) | FTOMAPTMEN1HTTKMT2A | |
| Fluorescein SCHEMBL3508466 | 0.81 | FTO (0.89) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL22639517 | 0.81 | FTO (0.66) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL29589246 | 0.81 | FTO (0.66) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL18461840 | 0.80 | FTO (0.77) | FTOMAPTMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494168-A1 | POLYMER COMPOSITIONS CONTAINING GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE | Johnson & Johnson Vision Care Inc. (US) | 2019-06-12 | — | — | EP | disclosed |
| WO-2018026822-A1 | POLYMER COMPOSITIONS CONTAINING GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2018-02-08 | — | — | WO | disclosed |