Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 4/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29815056 | 1.00 | FTO (1.00) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL14860604 | 0.92 | FTO (0.86) | FTOHPGDMEN1MAPTCYP2C19 | |
| Fluorescein SCHEMBL19839408 | 0.92 | FTO (0.85) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL18461840 | 0.87 | FTO (0.77) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL543293 | 0.85 | FTO (1.00) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL29938908 | 0.85 | FTO (1.00) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL4600340 | 0.85 | FTO (0.79) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL12500117 | 0.83 | FTO (0.80) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL31676645 | 0.83 | FTO (0.80) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL14213150 | 0.83 | FTO (0.79) | FTOHPGDMEN1MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12331146-B2 | Polymer compositions containing grafted polymeric networks and processes for their preparation and use | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2025-06-17 | — | — | US | disclosed |
| US-20240043598-A1 | POLYMER COMPOSITIONS CONTAINING GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE | JOHNSON & JOHNSON VISION CARE (US) | 2024-02-08 | — | — | US | disclosed |
| US-20240018294-A1 | OPHTHALMIC DEVICES DERIVED FROM GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE | JOHNSON & JOHNSON VISION CARE (US) | 2024-01-18 | — | — | US | disclosed |
| US-20240018294-A1 | OPHTHALMIC DEVICES DERIVED FROM GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE | JOHNSON & JOHNSON VISION CARE (US) | 2024-01-18 | — | — | US | disclosed |
| US-20240018294-A1 | OPHTHALMIC DEVICES DERIVED FROM GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE | JOHNSON & JOHNSON VISION CARE (US) | 2024-01-18 | — | — | US | disclosed |
| US-11834547-B2 | Ophthalmic devices derived from grafted polymeric networks and processes for their preparation and use | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| US-11820850-B2 | Polymer compositions containing grafted polymeric networks and processes for their preparation and use | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-11820850-B2 | Polymer compositions containing grafted polymeric networks and processes for their preparation and use | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-11820850-B2 | Polymer compositions containing grafted polymeric networks and processes for their preparation and use | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-20210179766-A1 | OPHTHALMIC DEVICES DERIVED FROM GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE | JOHNSON & JOHNSON VISION CARE (US) | 2021-06-17 | — | — | US | disclosed |
| WO-2018026822-A1 | POLYMER COMPOSITIONS CONTAINING GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2018-02-08 | — | — | WO | disclosed |
| US-20180037690-A1 | POLYMER COMPOSITIONS CONTAINING GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE | JOHNSON & JOHNSON VISION CARE, INC. | 2018-02-08 | — | — | US | disclosed |
| US-20180037690-A1 | POLYMER COMPOSITIONS CONTAINING GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE | JOHNSON & JOHNSON VISION CARE, INC. | 2018-02-08 | — | — | US | disclosed |
| US-6229055-B1 | SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES | MOLECULAR PROBES, INC. | 2001-05-08 | — | — | US | disclosed |
| US-6162931-A | Fluorinated xanthene derivatives | MOLECULAR PROBES, INC. (US) | 2000-12-19 | — | — | US | disclosed |
| US-5922612-A | INDEPENDENT, REVERSIBLE FLUORESCENCE SPECTROMETRY OF SAMPLE USING TWO OPTICAL SENSORS COMPOSED OF A CARRIER EACH COATED WITH DIFFERENT WATER INSOLUBLE BUT HYDROPHILIC ADDITION POLYMER LOADED WITH THE SAME FLUORESCENT DYE | NOVARTIS CORPORATION (US) | 1999-07-13 | — | — | US | disclosed |
| EP-0758451-B1 | OPTICAL SENSOR SYSTEM FOR DETERMINING pH VALUES AND IONIC STRENGTHS | NOVARTIS AG (CH) | 1999-01-20 | — | — | EP | disclosed |
| EP-0881241-A2 | Copolymers and dyes for optical pH sensors | Novartis AG (CH) | 1998-12-02 | — | — | EP | disclosed |
| EP-0758451-A1 | OPTICAL SENSOR SYSTEM FOR DETERMINING pH VALUES AND IONIC STRENGTHS | Novartis AG (CH) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030148-A1 | OPTICAL SENSOR SYSTEM FOR DETERMINING pH VALUES AND IONIC STRENGTHS | CIBA-GEIGY AG (CH) | 1995-11-09 | — | — | WO | disclosed |