Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 12/20 | 0.57 |
| ▸ | NMT2 | O60551 | 11/20 | 0.57 |
| ▸ | MC4R | P32245 | 3/20 | 0.57 |
| ▸ | MC1R | Q01726 | 3/20 | 0.57 |
| ▸ | MC3R | P41968 | 2/20 | 0.56 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | METAP1 | P53582 | 1/20 | 0.51 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | MC5R | P33032 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19839703 | 1.00 | NMT1 (0.57) | NMT1NMT2MC4RMC1RMC3R | |
| Hydrochloric Acid SCHEMBL19839690 | 0.99 | NMT1 (0.56) | NMT1NMT2MC4RMC1RMC3R | |
| Hydrochloric Acid SCHEMBL19839689 | 0.99 | NMT1 (0.56) | NMT1NMT2MC4RMC1RMC3R | |
| SCHEMBL19839628 | 0.90 | MC4R (0.55) | NMT1NMT2MC4RMC1RMC3R | |
| SCHEMBL19839630 | 0.90 | MC4R (0.55) | NMT1NMT2MC4RMC1RMC3R | |
| SCHEMBL28291231 | 0.90 | MC4R (0.57) | NMT1NMT2MC4RMC1RMC3R | |
| SCHEMBL19851498 | 0.85 | MC4R (0.51) | NMT1NMT2MC4RMC1RMC3R | |
| SCHEMBL28291262 | 0.79 | MC4R (0.57) | MC4RMC1RMC3RTLR2MC5R | |
| SCHEMBL19839775 | 0.78 | MC4R (0.57) | MC4RMC1RMC3RTLR2MC5R | |
| SCHEMBL19839774 | 0.78 | MC4R (0.57) | MC4RMC1RMC3RTLR2MC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3493814-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | Neuropore Therapies, Inc. (US) | 2019-06-12 | — | — | EP | claimed |
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | claimed |
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |