Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.51 |
| ▸ | MC1R | Q01726 | 2/20 | 0.51 |
| ▸ | MC3R | P41968 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | NMT2 | O60551 | 5/20 | 0.43 |
| ▸ | NMT1 | P30419 | 5/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19839628 | 0.88 | MC4R (0.55) | MC4RMC1RMC3RBCHEMETAP2 | |
| SCHEMBL19839630 | 0.88 | MC4R (0.55) | MC4RMC1RMC3RBCHEMETAP2 | |
| SCHEMBL19839703 | 0.85 | NMT1 (0.57) | MC4RMC1RMC3RBCHEMETAP2 | |
| SCHEMBL19839702 | 0.85 | NMT1 (0.57) | MC4RMC1RMC3RBCHEMETAP2 | |
| SCHEMBL19851733 | 0.85 | MC4R (0.53) | MC4RMC1RMC3RCTSBCTSS | |
| SCHEMBL19839742 | 0.85 | MC4R (0.52) | MC4RMC1RMC3RCTSBCTSS | |
| SCHEMBL19839739 | 0.85 | MC4R (0.52) | MC4RMC1RMC3RCTSBCTSS | |
| Hydrochloric Acid SCHEMBL19839690 | 0.84 | NMT1 (0.56) | MC4RMC1RMC3RBCHEMETAP2 | |
| Hydrochloric Acid SCHEMBL19839689 | 0.84 | NMT1 (0.56) | MC4RMC1RMC3RBCHEMETAP2 | |
| SCHEMBL28291231 | 0.84 | MC4R (0.57) | MC4RMC1RMC3RBCHECTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |