Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16163751 | 0.85 | ELANE (0.46) | LMNATSHRIRAK4NPC1RAB9A | |
| SCHEMBL1828510 | 0.84 | KMT2A (0.41) | LMNATSHRIRAK4NPC1RAB9A | |
| SCHEMBL5058437 | 0.80 | TDP1 (0.46) | IRAK4KMT2AMEN1ATMALDH1A1 | |
| SCHEMBL3199566 | 0.80 | KMT2A (0.51) | LMNAIRAK4KMT2ASMN1; SMN2ATM | |
| SCHEMBL28842455 | 0.80 | TSHR (0.46) | TSHRIRAK4KMT2AGAASMN1; SMN2 | |
| SCHEMBL8399530 | 0.80 | CA1 (0.45) | LMNATSHRIRAK4KMT2AMEN1 | |
| SCHEMBL7976424 | 0.80 | KMT2A (0.51) | LMNAIRAK4KMT2ASMN1; SMN2ATM | |
| SCHEMBL5062924 | 0.80 | TDP1 (0.46) | IRAK4KMT2AMEN1ATMALDH1A1 | |
| SCHEMBL1983875 | 0.80 | TSHR (0.46) | TSHRIRAK4KMT2AGAASMN1; SMN2 | |
| SCHEMBL27632858 | 0.79 | KMT2A (0.43) | LMNATSHRNPC1RAB9AGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104583235-B | Antibodies comprising site-specific unnatural amino acid residues, methods of making and using the same | 苏特罗生物制药公司 | 2019-03-01 | — | — | CN | claimed |
| CN-109311942-A | Angiotensin-1 receptor antagonists | 辉凌公司 | 2019-02-05 | — | — | CN | claimed |
| CN-109069664-A | anti-CD 74 antibody conjugates, compositions comprising anti-CD 74 antibody conjugates, and methods of use of anti-CD 74 antibody conjugates | 苏特罗生物制药公司 | 2018-12-21 | — | — | CN | claimed |
| CN-105723219-B | Recombinant microorganism and its application method | 朗泽科技新西兰有限公司 | 2018-06-05 | — | — | CN | claimed |
| CN-105238825-A | Method for producing optically active phenylalanine compounds from cinnamic acid derivatives employing a phenylalanine ammonia lyase derived from idiomarina loihiensis | DSM IP ASSETS BV | 2016-01-13 | — | — | CN | claimed |
| CN-102224238-B | Non-natural amino acid replication-dependent microorganisms and vaccines | AMBRX INC | 2015-06-10 | — | — | CN | claimed |
| EP-2723387-A1 | CATHEPSIN-BINDING COMPOUNDS BOUND TO A CARRIER AND THEIR DIAGNOSTIC USE | J. Stefan Institute (SI) | 2014-04-30 | — | — | EP | claimed |
| WO-2012175223-A1 | CATHEPSIN-BINDING COMPOUNDS BOUND TO A CARRIER AND THEIR DIAGNOSTIC USE | J. STEFAN INSTITUTE (SI) | 2012-12-27 | — | — | WO | claimed |
| CN-101517089-A | Method for producing optically active phenylalanine compound from cinnamic acid derivative using phenylalanine ammonia lyase derived from Idiomarina loihiensis | DSM IP ASSETS BV (NL) | 2009-08-26 | — | — | CN | claimed |
| CN-101511856-A | Suppressor TRNA transcription in vertebrate cells | AMBRX INC (US) | 2009-08-19 | — | — | CN | claimed |
| CN-101238143-A | Incorporation of non-naturally encoded amino acids into proteins | AMBRX INC (US) | 2008-08-06 | — | — | CN | claimed |
| CN-101223272-A | Expanding the eukaryotic genetic code | SCRIPPS RESEARCH INST (US) | 2008-07-16 | — | — | CN | claimed |
| EP-1490483-A2 | IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS | The Scripps Research Institute (US) | 2004-12-29 | — | — | EP | claimed |
| WO-2002085923-A2 | IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2002-10-31 | — | — | WO | claimed |
| CN-1362967-A | D-amino acid-containing regulator of beta-amyloid peptide aggregation | PRAECIS PHARM INC (US) | 2002-08-07 | — | — | CN | claimed |
| CN-113396218-B | Engineered transaminase polypeptides | 科德克希思公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-110536694-A | For treating pulmonary inflammatory composition and method | ATYR PHARMA INC | 2019-12-03 | — | — | CN | disclosed |
| CN-1320426-A | Compounds for the treatment of female sexual dysfunction | PFIZER (US) | 2001-11-07 | — | — | CN | disclosed |
| CN-1227494-A | Therapeutic applications of T-BAM (CD40L) technology to treat diseases involving smooth muscle cell | UNIV COLUMBIA (US) | 1999-09-01 | — | — | CN | disclosed |
| CN-1051914-A | The peptide class | MERRELL DOW PHARMA | 1991-06-05 | — | — | CN | disclosed |