Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16163751 | 0.87 | ELANE (0.46) | KMT2AMEN1GAAATMSMN1; SMN2 | |
| SCHEMBL1983996 | 0.84 | LMNA (0.39) | KMT2AMEN1GAAATMSMN1; SMN2 | |
| SCHEMBL27632858 | 0.81 | KMT2A (0.43) | KMT2AMEN1GAAATMSMN1; SMN2 | |
| SCHEMBL28036322 | 0.81 | GRM4 (0.42) | KMT2AMEN1GAAATMSMN1; SMN2 | |
| SCHEMBL31621484 | 0.79 | ELANE (0.46) | KMT2AMEN1GAAATMSMN1; SMN2 | |
| SCHEMBL3361719 | 0.79 | KMT2A (0.53) | KMT2AATMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL352382 | 0.79 | CA1 (0.47) | KMT2AMEN1GAASMN1; SMN2LMNA | |
| SCHEMBL1343624 | 0.79 | ELANE (0.46) | KMT2AMEN1GAAATMSMN1; SMN2 | |
| SCHEMBL1826831 | 0.79 | TDP1 (0.47) | KMT2AMEN1ATMALDH1A1KDM4E | |
| SCHEMBL1822201 | 0.78 | ALDH1A1 (0.49) | KMT2AMEN1GAASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2327766-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-12-02 | — | — | EP | disclosed |
| EP-2319919-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-1576108-B1 | NITRILASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | BASF ENZYMES LLC (US) | 2015-07-08 | — | — | EP | disclosed |
| EP-2327767-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-04-29 | — | — | EP | disclosed |
| EP-2327765-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-04-01 | — | — | EP | disclosed |
| CN-1849391-B | Nitrilases, nucleic acids encoding nitrilases, and methods of making and using the same | DIVERSA CORP | 2014-06-11 | — | — | CN | disclosed |
| EP-2115153-B1 | NITRILASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | BP CORP NORTH AMERICA INC (US) | 2013-06-05 | — | — | EP | disclosed |
| CN-102796750-A | Nitrilases, nucleic acids encoding them and methods for making and using Them | VERENIUM CORP | 2012-11-28 | — | — | CN | disclosed |
| CN-101528707-B | 2- [ 1-phenyl-5-hydroxy or methoxy-4 alpha-methyl-hexahydrocyclopenta [ f ] indazol-5-yl ] ethylphenyl derivatives useful as glucocorticoid receptor ligands | MERCK SHARP & DOHME | 2012-11-07 | — | — | CN | disclosed |
| EP-2327766-A1 | Nitrilases | Verenium Corporation (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2327767-A1 | Nitrilases | Verenium Corporation (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2327765-A1 | Nitrilases | Verenium Corporation (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2319919-A1 | Nitrilases | Verenium Corporation (US) | 2011-05-11 | — | — | EP | disclosed |
| CN-101528707-A | 2- [ 1-phenyl-5-hydroxy or methoxy-4 alpha-methyl-hexahydrocyclopenta [ f ] indazol-5-yl ] ethylphenyl derivatives useful as glucocorticoid receptor ligands | MERCK & CO INC (US) | 2009-09-09 | — | — | CN | disclosed |
| EP-2039762-A2 | Nitralases | Verenium Corporation (US) | 2009-03-25 | — | — | EP | disclosed |
| CN-1849391-A | Nitrilases, nucleic acids encoding nitrilases, and methods of making and using the same | DIVERSA CORP (US) | 2006-10-18 | — | — | CN | disclosed |