Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HINT1 | P49773 | 3/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 3/20 | 0.37 |
| ▸ | PDE1A | P54750 | 3/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12920214 | 0.95 | TAS1R3 (0.45) | TAS1R3TAS1R1POLA1KDM4EMEN1 | |
| SCHEMBL412282 | 0.95 | TAS1R3 (0.45) | TAS1R3TAS1R1POLA1KDM4EMEN1 | |
| SCHEMBL3180060 | 0.91 | POLA1 (0.54) | TAS1R3TAS1R1POLA1KDM4EHINT1 | |
| SCHEMBL12729619 | 0.91 | POLA1 (0.54) | TAS1R3TAS1R1POLA1KDM4EHINT1 | |
| SCHEMBL3180065 | 0.91 | POLA1 (0.54) | TAS1R3TAS1R1POLA1KDM4EHINT1 | |
| SCHEMBL19840345 | 0.83 | ADORA3 (0.47) | — | |
| SCHEMBL13930552 | 0.83 | POLA1 (0.49) | TAS1R3TAS1R1POLA1KDM4EHINT1 | |
| SCHEMBL3188499 | 0.83 | POLA1 (0.41) | TAS1R3TAS1R1POLA1KDM4EMEN1 | |
| SCHEMBL14062476 | 0.81 | KMT2A (0.43) | TAS1R3TAS1R1MEN1KMT2ATSHR | |
| SCHEMBL1971985 | 0.81 | TAS1R3 (0.56) | TAS1R3TAS1R1HINT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884885-B2 | Synthesis of labile base protected-modified deoxy and modified ribo nucleosides, corresponding phosphoramidites and supports and their use in high purity oligonucleotide synthesis | CHEMGENES CORPORATION (US) | 2018-02-06 | — | — | US | disclosed |