Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19840414 | 0.95 | KMT2A (0.48) | KMT2AATMTLR9MEN1ALDH1A1 | |
| SCHEMBL136397 | 0.85 | KMT2A (0.64) | KMT2AATMTLR9MEN1ALDH1A1 | |
| SCHEMBL29460850 | 0.85 | KMT2A (0.64) | KMT2AATMTLR9MEN1ALDH1A1 | |
| SCHEMBL25820279 | 0.85 | KDM4E (0.53) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL8512975 | 0.84 | KMT2A (0.62) | KMT2AATMTLR9MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8505910 | 0.84 | KMT2A (0.62) | KMT2AATMTLR9MEN1ALDH1A1 | |
| Iodide SCHEMBL29597673 | 0.84 | KMT2A (0.62) | KMT2AATMTLR9MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7049504 | 0.84 | KMT2A (0.62) | KMT2AATMTLR9MEN1ALDH1A1 | |
| Iodide SCHEMBL18040116 | 0.84 | KMT2A (0.62) | KMT2AATMTLR9MEN1ALDH1A1 | |
| SCHEMBL341793 | 0.82 | KMT2A (0.64) | KMT2AATMTLR9MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002790-A1 | POLY(Beta-AMINO ESTER) NANOPARTICLES FOR THE NON-VIRAL DELIVERY OF PLASMID DNA FOR GENE EDITING AND RETINAL GENE THERAPY | THE JOHNS HOPKINS UNIVERSITY | 2023-01-05 | — | — | US | disclosed |
| US-9884118-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-02-06 | — | — | US | disclosed |
| US-9884118-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-02-06 | — | — | US | disclosed |