Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19840900 | 0.84 | DPP4 (0.42) | KDM4EALDH1A1HDAC1RAB9ANPC1 | |
| SCHEMBL19840925 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10HDAC1 | |
| SCHEMBL19840905 | 0.81 | HPGDS (0.30) | — | |
| SCHEMBL19840691 | 0.81 | KMT2A (0.47) | KDM4EALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL19841151 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL19840881 | 0.80 | NTRK3 (0.33) | — | |
| SCHEMBL19840889 | 0.79 | CYP11B1 (0.39) | HDAC1 | |
| SCHEMBL19841145 | 0.79 | PDE10A (0.38) | — | |
| SCHEMBL19841015 | 0.79 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL19840878 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884832-B2 | Inhibitors targeting drug-resistant influenza A | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-02-06 | — | — | US | disclosed |