Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19840889 | 0.87 | CYP11B1 (0.39) | HPGDS | |
| SCHEMBL19840888 | 0.83 | LTA4H (0.40) | HDAC8 | |
| SCHEMBL19840778 | 0.82 | HDAC1 (0.36) | HPGDS | |
| SCHEMBL19840881 | 0.82 | NTRK3 (0.33) | — | |
| SCHEMBL19841145 | 0.81 | PDE10A (0.38) | — | |
| SCHEMBL19840940 | 0.81 | KDM4E (0.34) | — | |
| SCHEMBL19840884 | 0.80 | HDAC8 (0.47) | HDAC8 | |
| SCHEMBL19840811 | 0.79 | HPGDS (0.38) | HPGDS | |
| SCHEMBL19840900 | 0.79 | DPP4 (0.42) | HDAC8 | |
| SCHEMBL19840925 | 0.78 | KDM4E (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884832-B2 | Inhibitors targeting drug-resistant influenza A | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-02-06 | — | — | US | disclosed |