Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170379 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| SCHEMBL1170377 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| SCHEMBL22557798 | 0.75 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| SCHEMBL7718087 | 0.75 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| SCHEMBL19851313 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL7828453 | 0.73 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| SCHEMBL10398664 | 0.73 | MEN1 (0.48) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| SCHEMBL10398663 | 0.73 | MEN1 (0.48) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| SCHEMBL6382150 | 0.73 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 | |
| SCHEMBL173301 | 0.72 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037598-A1 | METHODS OF MAKING AND USING LIGNIN DERIVATIVES | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037598-A1 | METHODS OF MAKING AND USING LIGNIN DERIVATIVES | HLCS, LOX, DCXR | ALDH1A1 247/4885SMN1; SMN2 4440/4885CYP3A4 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.