Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 16/20 | 0.62 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19848034 | 0.92 | MGLL (0.52) | MGLLNR3C2TP53PKM | |
| SCHEMBL19833794 | 0.91 | MGLL (0.67) | MGLLNR3C2 | |
| SCHEMBL22386265 | 0.87 | MGLL (0.70) | MGLLNR3C2 | |
| SCHEMBL19833979 | 0.86 | MGLL (0.66) | MGLLNR3C2 | |
| SCHEMBL19848040 | 0.86 | MGLL (0.45) | MGLLTP53PKM | |
| SCHEMBL19833803 | 0.85 | MGLL (0.79) | MGLLNR3C2 | |
| SCHEMBL19847964 | 0.85 | MGLL (0.44) | MGLLTP53PKM | |
| SCHEMBL19847923 | 0.85 | MGLL (0.66) | MGLLNR3C2 | |
| SCHEMBL19833877 | 0.84 | MGLL (0.59) | MGLLNR3C2 | |
| SCHEMBL19833712 | 0.84 | MGLL (0.65) | MGLLNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279191-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2020-09-02 | — | — | EP | disclosed |
| EP-3279191-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-07 | — | — | EP | disclosed |